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Cyagen Cryopreservation offers fast and reliable methods for archiving embryos and sperm.
Cryoperservation of embryos and/or sperm is an ideal solution to maintain a live animal colony for strains that are rarely used. This backup can save significant space and prevent loss due to disease or in case an issue arises within your animal facility, providing an alternative to manage the colonies that will be used for research. Cyagen can back up your live animal colony by our embryo and sperm cryopreservation services, which can not only protect your valuable strains but also reduce your cost in the long run. We also can produce live animals for you in eight to twelve weeks once your cryopreserved stock is preserved at Cyagen.
Service Description Delieverables
Embryo Cryopreservation Mouse At least 200 two-cell embroys/line
Embryo Cryopreservation Mouse 8-10 straws of sperm/line
Service Description Delieverables
Embryo Reconstitution Mouse Minimum 2 heterozygous animals
Sperm Reconstitution Mouse Minimum 2 heterozygous animals
Cyagen Transgenic Animal Center

Provide breeding colonies of mice/rats

Cyagen Transgenic Animal Center (CTAC) is a specific-pathogen free (SPF) barrier facility. It houses 6,000-7,000 cages of mice in an ultra-clean environment. The facility’s housing space is divided into multiple separate barrier areas, each with its own restricted access, ventilation system, and husbandry staff. Cyagen’s breeding service provides reliable, economical, and efficient breeding colonies of mice/rats to support your research needs. All animal work is conducted in our specific pathogen free (SPF) facilities that have been AAALAC accredited and OLAW assured.
●  AAALAC accredited and OLAW assured
●  Specific-pathogen free (SPF) animal health status
●  
Individually ventilated cage (IVC) and exhaust ventilated cage (EVC) systems that can house up to 60,000 mice and 2,000 rats
●  Class 10,000 ultra-clean environment
●  Quarterly sentinel rodent health monitoring program
●  Quarantine for all incoming rodents prior to colony integration
Cyagen offers

 Transgenic founder mice/rats breeding to F1 

Description Delieverables Turnaround Time
Mouse A minimum of 2 F1 animals per line ~3 months
Rat A minimum of 2 F1 animals per line ~3 months

 ES cell gene targeted heterozygous mice breeding to homozygous mice 

Description Delieverables Turnaround Time
Standard 2~4 homozygous mice ~3 months
flox/flox 2~4 flox/flox mice ~3 months
tissue-specific KO/KO and KI/KI 2~4 tissue-specific KO/KO (or KI/KI) mice ~3 months

 CRISPR-mediated genome editing mice/rats breeding 

Description Delieverables Turnaround Time
Heterozygous A minimum of 3 heterozygotes ~3 months
Homozygous A minimum of 2 per line ~4 months