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Research Trends
What is Familial Exudative Vitreoretinopathy (FEVR)? What are the mouse models for it?
Aug 31, 2023
Familial Exudative Vitreoretinopathy (FEVR) is a group of rare hereditary retinal disorders characterized by abnormal retinal vascular development, leading to incomplete peripheral retinal vascularization and subsequent retinal ischemia. Read More >
Research Trends
Can Childhood Metabolic Disorders Actually Lead to Heart Failure? Gene Therapy Research Provides Hope
Aug 18, 2023
Have you ever encountered patients who, despite growing normally during early childhood, gradually begin to exhibit symptoms such as facial abnormalities, growth retardation, delayed intellectual development, skeletal deformities, neurological abnormalities, and cardiac involvement? Read More >
Research Trends
Recommended Classic Mouse Models for Metabolic and Cardiovascular Diseases! Double Assurance with Validation Data and Efficacy Evaluation System
Aug 11, 2023
Cardiovascular diseases are now the leading cause of death worldwide, posing a significant threat to human health. In China alone, there are approximately 330 million people with cardiovascular disease and 450 million with metabolic disease. Read More >
Latest Discovery
Igniting Momentum: GCT Industry Rekindles in 2023, Poised for Success
Jul 28, 2023
According to the latest quarterly report from ASGCT (American Society of Gene & Cell Therapy) , Q2 2023 proved to be a notable quarter in the field of therapy approvals, with the introduction of six new therapies that garnered regulatory clearance. Read More >
Ten Deadly Sins of Rare Diseases
Reviewing Muscular Dystrophy: Types, Pathology, and Gene Therapy Research [Ten Deadly Sins of Rare Diseases Ⅳ]
Jul 24, 2023
Step into the 'Ten Deadly Sins of Rare Diseases' series, where we unlock the mechanisms of occurrence and development of rare diseases, research advancements in the field of gene therapy, and innovative preclinical strategies related to model development and drug screening that drive translation of outcomes. Read More >
Ten Deadly Sins of Rare Diseases
The TARDBP gene is closely associated with pathogenesis of amyotrophic lateral sclerosis (ALS), but is it an angel or a demon? [Ten Deadly Sins of Rare Diseases Ⅲ]
Jul 14, 2023
Step into the 'Ten Deadly Sins of Rare Diseases' column, where we unravel the mechanisms underlying the occurrence and development of rare diseases, delve into gene therapy advancements, and explore innovative preclinical model development and drug screening strategies to drive effective translational research outcomes. Read More >
Ten Deadly Sins of Rare Diseases
Why are humanized mice more suitable for hemophilia research, which has a higher prevalence in men? [Ten Deadly Sins of Rare Diseases Ⅱ]
Jul 07, 2023
Rare diseases have always been a big challenge in the field of medical science. Noy only do these diseases have complex mechanisms of occurrence and different types, but importantly, there are no suitable animal models for studying the underlying pathogenesis and evaluating efficacy of drugs. Read More >
Ten Deadly Sins of Rare Diseases
Exploring RHO-Related Pathogenic Mechanisms and RHO Gene Therapy Research Progress [Ten Deadly Sins of Rare DiseasesⅠ]
Jun 30, 2023
June 6th, 2023 is the 28th National Eye Care Day of China. Do you know the theme of this year's Eye Care Day? Read More >
Research Trends
What are the Best Transgenic Animal Models for Alzheimer's Disease Research?
Jun 20, 2023
When it comes to Alzheimer's disease (AD), people may think of various emotional scenes portrayed in movies and TV shows. However, the reality is much more cruel, as we can see from the trending topic“They Will Forget Love And They Will Forget You”. Read More >
Research Trends
Common Mouse Models for Preclinical Alzheimer's Disease Research
Jun 15, 2023
After being diagnosed with Alzheimer’s in his later years, the famous British fantasy author Terry Pratchett described the disease in his writings: “On the first day of my journalistic career I saw my first corpse… All I can say is that, compared with his horrific demise, Alzheimer's is a walk in the park. Except with Alzheimer's my park keeps changing. The trees get up and walk over there, the benches go missing and the paths seem to be unwinding into particularly vindictive serpents.”. Read More >