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ES cell-based conditional knockout mice | AlphaKnockout Gene Targeting Expert System

AlphaKnockout - Free strategy designing tool
Genetically modified mice generated by gene targeting technologies such as ES targeting or CRISPR/Cas9 have been widely used to study gene functions and human diseases. However, even for sophisticated life scientists, it takes many hours of hard research to come up with a good gene targeting strategy. Cyagen’s gene targeting AI (artificial intelligence) expert system - AlphaKnockout can help you overcome these limitations - its fast, intelligent, reliable, reproducible, and best of all, free.

AlphaKnockout - Design your conditional knockout/knockin strategies for free
ES cell-based conditional knockout mice - TurboKnockout mice

TurboKnockout® - Fastest ES-cell based gene targeting approach
Cyagen offers a one-stop solution for animal model generation. In addition to free strategy designing with AlphaKnockout, TurboKnockout®, Cyagen's proprietary and the fastest ES-cell based gene targeting platform in the world, also allows you to generate conditional knockout/knockin mouse models in as short as 6 months, 4-6 months shorter than the standard approaches.

Now, any order for TurboKnockout® will enjoy 20% discounts, including free cryopreservation of strains.

Promotion Period: Sep 1, 2018 - Oct 31, 2018 Eligibility: End clients in Europe and North America

Service Turnaround Deliverables
Conditional knockout/knockin mice 6-8 months 4 TurboKnockout® mice

How to Order?

Europe: 800-793-45 or +32-28085797 (Int'l)
US: 800-921-8930 or +1 408-969-0306 (Int'l)

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——— Highlights of TurboKnockout® ———
Item TurboKnockout® Traditional ES Cell Targeting
Turnaround 6-8 months 10-14 months
F0 founders 100% ES cell derived Chimeras partially
Self-deleting selection cassette Yes No
Potential off-site target effects No No
Ability to introduce large fragment Yes Yes
Germline guarantee Yes Yes
Faster Turnaround with TurboKnockout® ES cell targeting

Faster Turnaround with
TurboKnockout®:

● TurboKnockout® ES cell targeting: 6~8 months

TurboKnockout® ES cell conditional knockout mice

● Traditional ES cell targeting: 10~14 months

Traditional ES cell conditional knockout
——— Cyagen’s Advantages ———
Over 12 years of experience in custom animal model generation

Over 12 years of experience
in custom animal model
generation

Working with over 1,000 bioscience institutions throughout the world

Working with over 1,000
bioscience institutions
throughout the world

Over 2,300 citations in SCI journals

Over 2,300 citations
in SCI journals

Over 26,000 animal models delivered to date

Over 26,000 animal models
delivered to date

Our facility can house up to 150,000 SPF strains

Our facility can house up to
150,000 SPF strains