Alpl-NLS-mScarlet
Product ID:
C001746
Background:
C57BL/6JCya
Documents:
Expressing Tissues/Cells:
Liver, kidney, bone tissue, placenta, intestine, and Alpl-positive cells
Product Type
Age
Genotype
Sex
Quantity
Price:
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Basic Information
Model Name
Alpl-NLS-mScarlet
Product ID
C001746
Gene Name
Background
C57BL/6JCya
Gene Alias
ALP; Akp2; TNAP; Akp-2; APTNAP; TNSALP
Classification
Reporter Mouse Lines
NCBI ID
Phenotype
Chromosome
4
Document
Note: When using this mouse strain in a publication, please cite “Alpl-NLS-mScarlet mice (Catalog C001746) were purchased from Cyagen.”
Strain Description
The P2A-3xSV40 NLS-mScarlet cassette was inserted upstream of TGA stop codon. Nuclear-localized mScarlet is expressed under the regulatory control of Alpl gene elements in this mouse model, without impacting endogenous Alpl gene expression. This localization is achieved through the Nuclear Localization Signal (NLS), which efficiently targets mScarlet to the cell nucleus. This enables mScarlet fluorescence protein nuclear tracing studies.
Validation Data