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Search Results for “”
Arteriosclerosis, Thrombosis, and Vascular Biology, March, 2026
Targeting Endothelial PDK4-EndoMT Feedback Loop Mitigates the Development of Thoracic Aortic Dissection in Mice
Metabolism and Cardiovascular
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Nature, March, 2026
Proteasome-guided haem signalling axis contributes to T cell exhaustion
Immunology
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Nature Communications, February, 2026
Amelioration of colorectal cancer-associated fibroblasts in immunosuppressive microenvironment by ferroptosis-based nanotherapy
Cancer
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CANCER RESEARCH, February, 2026
SAICAR Drives T Regulatory Cell Differentiation and FOXP3 Maintenance to Promote Immunotherapy Resistance
Immunology
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Nature Communications, February, 2026
Escherichia coli promotes colorectal cancer metastasis by maintaining enhancer-promoter loops through releasing neutrophil extracellular traps
Cancer
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Cell Death & Disease, January, 2026
RNASEH2C enhances TRAF3IP1 to degrade RAI14 in lysosomes thus hindering macrophage antigen presentation and advancing liver cancer
Cancer
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Nature Communications, January, 2026
Palmitic acid-triggered B7H3 palmitoylation promotes immune escape
Cancer
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Military Medical Research, November, 2025
TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice
Other
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Cell Reports, November, 2025
Vascular Lamb1 guides the migration of retinal microglial precursors via Itga6-Rac1 signaling
Other
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European heart journal, October, 2025
Targeting P2Y14R alleviates platelet-induced NET formation and venous thrombosis through PKA/AKAP13/RhoA axis
Other
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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