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Breeding Service
Cyagen offers professional mouse and rat breeding services to help you expand your colony efficiently and maintain genetic fidelity—saving you time, space, and operational overhead. Whether you're working with transgenic founders, knockout lines, or conditional models, our team ensures seamless delivery of healthy, correctly genotyped animals.
Flexible Options
Standard, conditional, or IVF-based breeding tailored to your needs.
SPF Plus Quality
Enhanced health and genetic monitoring in certified facilities.
End-to-End Support
From mating to genotyping, every breeding step is expertly managed.
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Overview
Breeding Programs for All Genetic Backgrounds
Cyagen supports the expansion of transgenic, KO/KI, conditional, and genome-edited rodent models. From founder screening to homozygote delivery, our team manages each step with precision.

All breeding is performed in AAALAC-accredited, SPF Plus facilities with strict health and genetic monitoring. Standardized workflows and regular updates ensure transparency, while flexible options—such as IVF-based rapid expansion or long-term colony maintenance—meet your evolving research needs.

Backed by industry-leading guarantees, our breeding services are designed for efficiency, accuracy, and peace of mind.
Explore Ready-to-Use Mouse Models
Discover over 18,000 validated mouse strains—including knockout, conditional knockout, and humanized models—covering 20+ research areas such as oncology, neurology, and metabolism. All models are supported by detailed genotype data and guaranteed quality, helping you fast-track discovery with confidence.
You Might Also Be Interested In
MouseAtlas Model Library
Search and access curated genetically engineered mouse strains
Cryopreservation & Recovery
Preserve and revive rodent strains on demand
Rodent Phenotyping
Full-spectrum analysis for rodents model
Turboknockout® Gene Editing
Fast-track your research with our efficient gene targeting service.
Knockout Cell Lines Library
Browse validated human KO cell lines by gene or cell type
Tumor Cell Lines Library
Access characterized human tumor lines by cancer type or genetic status.
Workflow
Workflow and Delivery
Our breeding services are structured to match your model’s genotype and research goals, with timelines adjusted according to project type. You can expect regular updates, PCR genotyping reports, and delivery of animals that meet your defined specifications.
Timeline Table
Breeding Type Typical Timeline Deliverables
F0 to F1 (Transgenic) ~3 months ≥2 F1 animals/line
Heterozygote to Homozygote (KO/KI) 3–6 months 2–4 Homozygotes
Conditional Breeding (Cre crosses) 5–9 months Flox/flox or KO/KO mice
IVF-based Rapid Expansion ~2 months ≥100 same-age animals
Colony Maintenance Monthly Custom schedule
FAQs
Frequently Asked Questions (FAQs)
What if no homozygotes are obtained from a breeding attempt?
If 30 pups are screened without yielding homozygotes, we will discuss potential embryonic lethality and consult with you on alternatives.
How do you ensure animal health during breeding?
We employ a robust SPF Plus monitoring system, with quarterly microbiological checks (internal and IDEXX), SOP-based handling, and clean environments.
Can I request large cohorts or synchronized litters?
Yes, we offer IVF-based rapid expansion services to generate large, same-age cohorts quickly.
Is long-term colony maintenance available?
Yes, we offer monthly per-line maintenance services with optional cryopreservation for backup.
Can I customize the breeding strategy for my project?
Absolutely. Our technical team can help design a breeding plan tailored to your genetic background, experimental goals, and timeline.
What Customers Say About Cyagen
Violet Shimmer
Stanford University
The service provided to us by Cyagen is now in press at Nature as an article.
Scarlett Rouge
Seattle Children’s Hospital
We are very pleased with the state-of-the-art professional transgenic services provided by Cyagen for our study published recently in Nature. We continue to use Cyagen’s transgenic services as it allows us to do better and more efficient research with transgenic mice.
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Connect with our experts for your custom animal model needs. Please fill out the form below to start a conversation or request a quote.
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