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Animal Models
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Humanized Immune Mice for Preclinical Immunotherapy
Blogs & Insights
Explore how HIS mice enable the in vivo evaluation of checkpoint inhibitors, bispecific antibodies, and cancer vaccines. These models replicate human immune-tumor interactions and help predict treatment outcomes more accurately than traditional mice.
Neuroscience CRO Services
Neuroscience
Cyagen provides one-stop neuroscience CRO solutions from custom animal model generation to behavioral and molecular efficacy evaluation, enabling precise, rapid, and reliable preclinical research.
Inducible Cre Mouse Enhances Pancreatic Gene Knockouts
Blogs & Insights
Achieve reliable pancreas-specific gene recombination with the Pdx1-CreERT2 model. This tamoxifen-inducible line improves over traditional Cre models by reducing background activity and increasing recombination efficiency in islet cells.
B6-hIGHMBP2 Mice Enable Gene Therapy Testing for CMT2S
Blogs & Insights
Learn how the B6-hIGHMBP2 humanized mouse model supports rare disease research for IGHMBP2-related conditions like SMARD1 and CMT2S. This model expresses the full human gene and enables evaluation of gene and nucleic acid therapies.
From Bench to Bedside: iPSCs in Modern Biomedicine
Blogs & Insights
See how induced pluripotent stem cells enable precision models for neurodegeneration, cardiac repair, immune cell therapy, and high-throughput drug discovery. These platforms provide scalable, human-relevant solutions for complex diseases.
Adipoq-iCre Mice for Targeted Fat Tissue Studies
Blogs & Insights
Discover how Adipoq-iCre mice enable precise gene targeting in white and brown adipose tissues. Learn how this model, when crossed with tdTomato reporters, supports clear fluorescent detection and enhances research on fat metabolism.
How IECs Use MHC II and PD-L1 to Guide T Cells
Blogs & Insights
Explore how intestinal epithelial cells regulate CD4+CD8αα+ IEL differentiation via MHC II and PD-L1 expression in response to IFN-γ and microbiota. Learn how Cyagen’s mouse models, including IEC-specific knockouts and GF mice, support immunological studies into gut barrier integrity and immune cell education.
Human IL-15 Mouse Models Enable NK Cell Immunotherapy R&D
Blogs & Insights
Discover how NKG-hIL15 and huHSC-NKG-hIL15 mice enable high-fidelity reconstitution of functional human NK cells. With stable expression of human IL-15, these models support in-depth evaluation of NK-targeted drugs, offering translational relevance and expanded immune functionality for preclinical research.
Flow Cytometry Applications in CAR-T Development
Blogs & Insights
Flow cytometry plays a critical role in preclinical CAR-T workflows, from target antigen validation and virus titer assessment to CAR expression, phenotyping, and in vivo tracking. Discover how Cyagen integrates this powerful technology across cell therapy pipelines to support rapid and reliable development.
Business Development Manager – Korea
Careers
Cyagen is seeking a dynamic and strategic Business Development Manager to lead market expansion efforts in South Korea. This role focuses on driving sales growth, building lasting customer relationships, and executing market-specific strategies to enhance Cyagen’s presence and revenue in the Korean life sciences sector.
Animal Models
C57BL/6NCya-Bnip3em1/Cya
KO/cKO Mouse Models
Bnip3 is located on chromosome 7 of mice. Nuclease Technology was used to design sgRNA; Bnip3 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Cav2em1/Cya
KO/cKO Mouse Models
Cav2 is located on chromosome 6 of mice. Nuclease Technology was used to design sgRNA; Cav2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Grk5em1/Cya
KO/cKO Mouse Models
Grk5 is located on chromosome 19 of mice. Nuclease Technology was used to design sgRNA; Grk5 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Syt7em1/Cya
KO/cKO Mouse Models
Syt7 is located on chromosome 19 of mice. Nuclease Technology was used to design sgRNA; Syt7 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Lap3em1/Cya
KO/cKO Mouse Models
Lap3 is located on chromosome 5 of mice. Nuclease Technology was used to design sgRNA; Lap3 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Tmem65em1/Cya
KO/cKO Mouse Models
Tmem65 is located on chromosome 15 of mice. Nuclease Technology was used to design sgRNA; Tmem65 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-1700113H08Rikem1/Cya
KO/cKO Mouse Models
1700113H08Rik is located on chromosome 10 of mice. Nuclease Technology will be used to design sgRNA; 1700113H08Rik knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Tubem1/Cya
KO/cKO Mouse Models
Tub is located on chromosome 7 of mice. Nuclease Technology was used to design sgRNA; Tub knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Mir142em1/Cya
KO/cKO Mouse Models
Mir142 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Mir142 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Il10em1/Cya
KO/cKO Mouse Models
Il10 is located on chromosome 1 of mice. Nuclease Technology was used to design sgRNA; Il10 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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