Fbl is related to the typing of Staphylococcus lugdunensis. fbl-typing can be used to distinguish different pathogenic phenotypes of S. lugdunensis. Compared with the Matrix-Assisted Laser Desorption/Ionization-Time-of-Flight Mass Spectrometry (MALDI-TOF MS) dendrogram, fbl-typing could better correspond to the pathogenic phenotype, with better recognition and reproducibility [1].

In the phylogenetic tree constructed in the fbl R-region, certain infection types showed a clustering tendency. New type 3 was the most dominant fbl-type, followed by fbl47b. Bone and joint infection isolates and ear infection isolates were significantly clustered together. All the oxacillin-resistant isolates were concentrated in fbl-type fbl45j and fbl47b [1].

In conclusion, fbl-typing of S. lugdunensis has characteristics such as convenient operation, low cost, and high repeatability, and can effectively indicate the pathogenic phenotype. Understanding fbl-typing helps in clarifying the epidemiological characteristics of S. lugdunensis and provides data support for further research on its pathogenicity and antimicrobial resistance [1].