Pard6g, while no common aliases are provided in the given references, is involved in various biological processes. In the osteoblast-lineage, it is part of a gene network. Perturbation of Pard6g expression affects osteoblast proliferation and differentiation, indicating its importance in skeletal development, growth, and maintenance [2].

Pard6g has also been associated with several diseases. In a study on frozen shoulder, it was found to have a positive causal relationship with the disease, suggesting that genetic predisposition to higher Pard6g expression levels may increase the risk of frozen shoulder [1]. A genome-wide association analysis in dystrophinopathy patients suggested Pard6g as a likely candidate modifier of disease severity, potentially through non-coding SNP regulatory effects [3]. In an analysis of gene expression profiles of lung cancer subtypes, Pard6g was identified as a differentially expressed gene between lung adenocarcinoma and lung squamous cell cancer [4].

In conclusion, Pard6g plays important roles in skeletal-related biological processes and is associated with diseases such as frozen shoulder, dystrophinopathy, and lung cancer. Understanding its function through in vivo studies and potentially gene knockout models could provide insights into the mechanisms of these diseases and may help develop targeted treatment strategies.