C57BL/6NCya-Ube2q2lem1/Cya
Common Name
Ube2q2l-KO
Product ID
S-KO-00118
Backgroud
C57BL/6NCya
Strain ID
KOCMP-100502936-Ube2q2l-B6N-VA
When using this mouse strain in a publication, please cite “Ube2q2l-KO Mouse (Catalog S-KO-00118) were purchased from Cyagen.”
Product Type
Age
Genotype
Sex
Quantity
Basic Information
Strain Name
Ube2q2l-KO
Strain ID
KOCMP-100502936-Ube2q2l-B6N-VA
Gene Name
Product ID
S-KO-00118
Gene Alias
E330021D16Rik
Background
C57BL/6NCya
NCBI ID
Modification
Conventional knockout
Chromosome
Chr 6
Phenotype
Datasheet
Application
--
Strain Description
Ensembl Number
ENSMUST00000204830
NCBI RefSeq
NM_001201390
Target Region
Exon 2
Size of Effective Region
~1.6 kb
Overview of Gene Research
Ube2q2l, details about its aliases and normal functions remain undetermined from the given reference. However, it's likely involved in biological processes relevant to breast cancer [1].
A study aimed to find gene sets related to breast cancer using differential co-expression and differential expression (DECODE). The optimal gene was identified as Ube2q2l with optimal thresholds for differential co-expression (DC) and differential expression (DE) being 2.254 and 1.616 respectively. Genes were partitioned based on these thresholds. Ube2q2l, within the HDE-HDC partition, had the highest minimum FI gain of 18.973. It was suggested that Ube2q2l and the "fatty acid catabolic process" gene set might be potentially useful diagnostic signatures for breast cancer [1].
In conclusion, Ube2q2l appears to have potential significance in breast cancer diagnosis, as indicated by the study using DECODE analysis. Its role within the context of breast cancer-related gene partitions and the "fatty acid catabolic process" gene set suggests it could be a valuable biomarker for breast cancer [1].
References:
1. Wang, Lei, Ma, Hong, Zhu, Lixia, Wei, Hui, Xu, Jumei. . Screening for the optimal gene and functional gene sets related to breast cancer using differential co-expression and differential expression analysis. In Cancer biomarkers : section A of Disease markers, 17, 463-471. doi:10.3233/CBM-160663. https://pubmed.ncbi.nlm.nih.gov/27802197/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen
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