C57BL/6JCya-Grpem1/Cya
Common Name
Grp-KO
Product ID
S-KO-05890
Backgroud
C57BL/6JCya
Strain ID
KOCMP-225642-Grp-B6J-VA
When using this mouse strain in a publication, please cite “Grp-KO Mouse (Catalog S-KO-05890) were purchased from Cyagen.”
Product Type
Age
Genotype
Sex
Quantity
Basic Information
Strain Name
Grp-KO
Strain ID
KOCMP-225642-Grp-B6J-VA
Gene Name
Product ID
S-KO-05890
Gene Alias
BLP
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
Chr 18
Phenotype
Datasheet
Application
--
Strain Description
Ensembl Number
ENSMUST00000025395
NCBI RefSeq
NM_175012
Target Region
Exon 2
Size of Effective Region
~0.2 kb
Overview of Gene Research
Grp, also known as Gastrin-releasing peptide, is a regulatory peptide. It plays a crucial role in various biological functions such as cell growth, differentiation, and neurotransmission. It is involved in the gastrin-releasing peptide receptor-mediated signaling pathway, which impacts multiple physiological processes [1]. Grp is of great biological importance as it has implications in several disease-related mechanisms. Genetic models, like KO/CKO mouse models, can be valuable for studying its functions.
However, the provided PubMed abstracts do not contain any information related to Grp.
In conclusion, while Grp has important functions in cell growth, differentiation, and neurotransmission through its associated signaling pathway, without relevant findings from the provided references, further research using KO/CKO mouse models is needed to fully understand its role in specific biological processes and disease conditions.
References:
1. Chen, Weibo, Wang, Zhongxia, Jiang, Chunping, Ding, Yitao. 2013. PP2A-Mediated Anticancer Therapy. In Gastroenterology research and practice, 2013, 675429. doi:10.1155/2013/675429. https://pubmed.ncbi.nlm.nih.gov/24307892/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen
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