C57BL/6JCya-Sval1em1/Cya
Common Name
Sval1-KO
Product ID
S-KO-13593
Backgroud
C57BL/6JCya
Strain ID
KOCMP-71578-Sval1-B6J-VA
When using this mouse strain in a publication, please cite “Sval1-KO Mouse (Catalog S-KO-13593) were purchased from Cyagen.”
Product Type
Age
Genotype
Sex
Quantity
Basic Information
Strain Name
Sval1-KO
Strain ID
KOCMP-71578-Sval1-B6J-VA
Gene Name
Product ID
S-KO-13593
Gene Alias
9130404C18Rik, SLP-C
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
Chr 6
Phenotype
Datasheet
Application
--
Strain Description
Ensembl Number
ENSMUST00000031898
NCBI RefSeq
NM_027832
Target Region
Exon 1~4
Size of Effective Region
~4.3 kb
Overview of Gene Research
Sval1 is a group of clone sequences most closely related to Desulfosarcina variabilis. These sequences are affiliated with the Desulfosarcina-Desulfococcus group of sulfate-reducing bacteria (SRB) in marine Arctic sediments [1]. In this context, Sval1-related SRB are part of the overall SRB community which is important for the sulfur cycle in these ecosystems.
In the marine Arctic sediment (Smeerenburgfjorden, Svalbard), the Sval1-affiliated SRB were dominant, accounting for up to 54.8% of the total SRB detected. The SRB community structure was characterized using fluorescence in situ hybridization (FISH) and rRNA slot blot hybridization. The rRNA contents of Desulfosarcina-Desulfococcus cells (including those related to Sval1) were highest near the sediment surface, indicating maximal metabolic activity there, and cellular sulfate reduction rates were also highest in the surface layer [1].
In conclusion, Sval1-related sulfate-reducing bacteria play a significant role in the metabolism and community structure of SRB in marine Arctic sediments. Understanding their function helps in comprehending the sulfur-cycling processes in these cold-water ecosystems.
References:
1. Ravenschlag, K, Sahm, K, Knoblauch, C, Jørgensen, B B, Amann, R. . Community structure, cellular rRNA content, and activity of sulfate-reducing bacteria in marine arctic sediments. In Applied and environmental microbiology, 66, 3592-602. doi:. https://pubmed.ncbi.nlm.nih.gov/10919825/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen
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