C57BL/6JCya-Slc5a9em1/Cya
Common Name:
Slc5a9-KO
Product ID:
S-KO-18797
Background:
C57BL/6JCya
Product Type
Age
Genotype
Sex
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Basic Information
Strain Name
Slc5a9-KO
Strain ID
KOCMP-230612-Slc5a9-B6J-VB
Gene Name
Product ID
S-KO-18797
Gene Alias
SGLT4
Background
C57BL/6JCya
NCBI ID
Modification
Conventional knockout
Chromosome
4
Phenotype
Document
Application
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Note: When using this mouse strain in a publication, please cite “C57BL/6JCya-Slc5a9em1/Cya mice (Catalog S-KO-18797) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000102721
NCBI RefSeq
NM_145551
Target Region
Exon 4~6
Size of Effective Region
~2.6 kb
Detailed Document
Overview of Gene Research
Slc5a9, also known as SGLT4, is a Na+-dependent glucose transporter. It plays a crucial role in the absorption and/or reabsorption of mannose, 1,5-anhydro-D-glucitol, and fructose, in addition to glucose [1]. This function places it in the context of carbohydrate metabolism pathways, and its importance lies in maintaining proper nutrient balance in the body. Functional studies of Slc5a9 in genetic models could potentially further elucidate its specific mechanisms.
No KO/CKO mouse model-related findings were present in the provided references.
In summary, Slc5a9 is an essential transporter for multiple sugars, contributing to carbohydrate-related physiological processes. While the lack of KO/CKO mouse model data in the given references limits in-depth understanding of its role in disease conditions, its function in sugar transport is a key aspect of its biological importance.
References：
1. Tazawa, Shigeki, Yamato, Tokuhisa, Fujikura, Hideki, Isogai, Takao, Isaji, Masayuki. . SLC5A9/SGLT4, a new Na+-dependent glucose transporter, is an essential transporter for mannose, 1,5-anhydro-D-glucitol, and fructose. In Life sciences, 76, 1039-50. doi:. https://pubmed.ncbi.nlm.nih.gov/15607332/
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen