Anapc13, while no common aliases are provided in the references, seems to function as a cell proliferation regulator. It may be involved in various biological processes, as its dysregulation is associated with different diseases, highlighting its overall biological importance. Genetic models, such as mouse models, could potentially be valuable for further studying its functions [1].

In a study on a cancer-associated SF3B1-K700E mutation, Treg-specific expression of this mutation led to autoimmune phenotypes. The mutation induced aberrant splicing of Anapc13, reducing its expression due to the insertion of a 231-base pair DNA fragment into the 5' untranslated region. Forced expression of Anapc13 restored the differentiation and function of Tregs, indicating that Anapc13 is crucial for Treg function and immune response regulation [1].

In conclusion, Anapc13 functions as a cell proliferation regulator and is essential for Treg-mediated immune response regulation. The study using the SF3B1-K700E mutation in a mouse model reveals its significance in the context of immune-related diseases, suggesting that understanding Anapc13's function may provide insights into immune-related disease mechanisms and potential therapeutic targets.