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buy one, get one 50% off on your next knockout/knockin and transgenic mouse/rat models

Cyagen is pleased to announce its largest animal model savings event of the year! Order any custom-made mouse or rat model and receive 50% off your second model (of equal or lesser value).

To take advantage of these great savings, mention promo code BOGO50 when requesting your free quote and gene targeting strategy! This promotion is valid through December 31, 2017.

TurboKnockout® Gene Targeting Mice: As fast as 6-8 months

Service Turnaround time Deliverables
TurboKnockout® (conditional KO/KI) 6-8 months 3 100% ES-cell derived founders, or their progeny

Highlights of TurboKnockout®:

Timeline comparable to nuclease-based genome editing (i.e., CRISPR, TALEN)
More flexible than nuclease mediated methods (e.g., conditional models, humanizations, ROSA26)
Guaranteed germline transmission
No off-target effects
Comparable cost to traditional ES cell methods

CRISPR/Cas9-based Knockout: Unrivaled speed and convenience

Service Turnaround time Deliverables
Knockout Mice ~5.5 months 3 F1
Knockout Rats ~6 months 3 F1

PiggyBac Transgenic Models: Single copy integration per integration site, more consistent gene expression compared to plasmid/BAC based approaches

Service Turnaround time Deliverables
PiggyBac Transgenic Mice ~3 months 3 F0
PiggyBac Transgenic Rats ~3 months 3 F0

TRIB3 Promotes APL Progression through Stabilization of the Oncoprotein PML-RARα and Inhibition of p53-Mediated Senescence.
Cancer Cell 31:697 (2017) IF=27.407

The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation by promoting proteasomal degradation of NLRP3.
IMMUNITY 47:107 (2017) IF=22.845

NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
Mol Cell PMID: 28943315 (2017) IF=14.714

Hierarchy within the mammary STAT5-driven Wapsuper-enhancer.
Nature Genetics 48:904 (2016) IF=27.959