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Research Trend
Do You Know About Gene Therapy Research?
Dec 01, 2021
What is Gene Therapy? Gene therapy aims to treat or cure genetic diseases through the introduction of foreign, normally-functioning genes into target cells to correct or compensate for defective or abnormal genes. Read More >
Research Trend
Uses of Humanized Mice in Tumor Immunotherapy Study
Nov 30, 2021
A PDX humanized mouse is engrafted with a human tumor, which we call a patient-derived xenograft (PDX). Read More >
Weekly Model
Gene Fgf20 Mouse Models and New Research Progress
Nov 26, 2021
In future studies, FGF20 may become a hot target for researchers of Parkinson’s disease. Genes perform a variety of functions, and FGF20 is no exception. Read More >
Research Trend
How Are Humanized Mice Made?
Nov 24, 2021
Humanized mice — engrafted with human tissues, cells, and/or genes — are a model for studying preclinical aspects of human ailments. Read More >
Weekly Gene
Parkinson's Disease (PD) and the FGF20 Gene
Nov 23, 2021
Parkinson's disease (PD) is a neurodegenerative disorder that predominantly affects dopamine-producing (“dopaminergic”) neurons in a specific area of the brain, called the substantia nigra. Read More >
Weekly Model
HNRNPC Mouse Models and New Research Progress
Nov 17, 2021
The establishment of these mouse models is helpful for research on the function of the hnRNP C1 and C2 proteins and the regulatory expression of the splicing factor hnRNP C. Insight into new research results Read More >
Weekly Gene
The "Culprit" Of the Rare Diseases MCTD/OPMD - HNRNPC
Nov 16, 2021
In this article, we review the hottest oncogene HNRNPC, hoping to give you insights on its role in rare disease development as a therapeutic target in MCTD research. Read More >
Weekly Gene
A Gene Related to Excitement- GRIA3
Nov 09, 2021
This week’s subject is the Glutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) gene, which is closely related to the feeling of excitement. Read More >
Weekly Gene
NLRP3 and Familial Cold Autoinflammatory Syndrome
Nov 02, 2021
The NLRP3 gene encodes NLR Family Pyrin Domain Containing 3 - a pyrin-like protein which contains a pyrin domain, a nucleotide binding site (NBS) domain, and a leucine-rich repeat sequence (LRR) motif. Read More >
Weekly Gene
An Important Target of the Deadly Lung Disease Idiopathic Pulmonary Fibrosis—CAV1
Oct 26, 2021
The CAV1 gene is responsible for encoding the Caveolin 1 (CAV1) protein, also called caveolin-1 (CAV-1), which belongs to the Caveolin family of integral membrane proteins. Read More >