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Research Trends
New Addition to Ophthalmic Models: Autosomal Recessive Retinitis Pigmentosa (arRP) - Rho KO Mice
Jun 06, 2025
Retinitis Pigmentosa (RP) is a group of inherited retinal degenerative diseases that affect over 1.5 million people worldwide. Read More >
Research Trends
World Thalassemia Day | Powerful Tool for Disease Research: Hbb-bs & Hbb-bt DKO Mouse Models
May 29, 2025
May 8 marks World Thalassemia Day — a timely opportunity to introduce β-thalassemia, a hereditary blood disorder caused by reduced or absent synthesis of the β-globin chains of hemoglobin. Read More >
Research Trends
On Huntington's Disease Awareness Day: How Humanized Models Drive Therapeutic Innovation
May 23, 2025
May 15 marks International Huntington's Disease Awareness Day — a date not only meant to raise public awareness for those affected but also to highlight the urgent need for breakthroughs in treating this devastating condition. Read More >
Research Trends
Gaa Knockout Mice: A Powerful Model for Accelerating Pompe Disease Research
May 15, 2025
Imagine a disease where the very substance meant to fuel your body—glycogen—becomes a silent saboteur, accumulating in critical tissues and gradually stealing a patient's strength and mobility. Read More >
Research Trends
World Lupus Day Spotlight: SLE Animal Models Driving Mechanistic Insights and Therapeutic Innovation
May 09, 2025
Recently, Fate Therapeutics announced that its allogeneic CAR-T cell therapy FT819, developed based on induced pluripotent stem cells (iPSCs), has been granted Regenerative Medicine Advanced Therapy (RMAT) designation by the FDA Read More >
Research Trends
Full-Spectrum SMA Models: Humanized Mice with Varying SMN2 Copy Numbers
Apr 30, 2025
Spinal Muscular Atrophy (SMA) remains one of the most devastating genetic diseases affecting infants and children worldwide. Read More >
Research Trends
Validating GLP-1RA Therapy in Preclinical Mouse Models of Metabolic Dysfunction-Associated Steatohepatitis
Apr 25, 2025
Discover how Cyagen's validated preclinical MASH mouse models are accelerating GLP-1RA therapeutic development through clinically relevant disease modeling and pharmacodynamic evaluation. Read More >
Research Trends
Newsletter
World Hemophilia Day | China Approves First AAV Gene Therapy Drug: How Humanized Animal Models Enable Breakthroughs in Rare Disease Treatment
Apr 17, 2025
On April 10, China’s National Medical Products Administration (NMPA) officially approved Dalnacogene Pankparvovec Injection (brand name: XinJiuning, research code: BBM-H901) Read More >
Research Trends
Preliminary Data: Inducible PKD Mouse Model Shows Phenotype in as Fast as 3 Weeks
Apr 11, 2025
ADPKD is the most common inherited kidney disorder worldwide and a major cause of end-stage kidney disease (ESKD). Read More >
Research Trends
HUGO Series Humanized Mice: Revolutionizing Antibody Discovery and Gene Therapy Research
Apr 03, 2025
An exclusive interview with Dr. Yingbin (Marvin) Ouyang, Executive Vice President and Chief Scientific Officer at Cyagen, on breakthrough advancements in humanized genomic ortholog mouse models. Read More >