The mouse model has become an irreplaceable model organism for biomedical research, which includes studying gene function and genetic factors of pathogenesis, establishing humanized disease models, and evaluating the safety and effectiveness of drugs under development. Read More ›

Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder, which affects 20 to 30 million individuals worldwide. Currently, no effective therapies to treat or cure this disease have been developed. In this review, we discuss the current research and understanding of the PSEN1 gene and its mutation which causes familial Alzheimer's disease (FAD). Read More ›

Happy Halloween from Cyagen! To celebrate and educate, our team has put together brief synopses of several genes related to fear: STMN1, P4H-TM, ANXA1, FPR1, DAGLA, and TAAR1. Read on to learn about each gene’s functions, research progress, and opportunities for discovery. Read More ›

Taconic Biosciences and Cyagen Biosciences have formed a strategic non-profit alliance. As partners, Taconic and Cyagen leverage the power of our complementary approaches to redefine the model generation customer experience by bringing the best and most competitive solutions to the market. Read More ›

Academic researchers interested in utilizing mouse or rat models are invited to apply for the Taconic-Cyagen Custom Animal Model Awards (CAMA) competition – offering a range of grant awards valued over $77,350 that will help fund six (6) custom animal model (CAM) project proposals anticipated to most significantly impact their respective research fields. Read More ›

It is well known that genes play a major role in many human diseases - for this reason they are an important research topic in the field of life science and medicine. How can the public quickly grasp the recent research on disease-related genes, when the only resources out about them are long complex academic journals? Read More ›

Animal modeling has a played a prominent role in traditional scientific research for hundreds of years. More recently, inbred strains have been developed to support genetically modified models – sometimes called the “living reagents” or “living instruments” of biomedical and health research. Read More ›

With the advantages of simple operation and high recombination rate, the Cre-Lox system has now become a powerful tool for genetic manipulation across in vivo and in vitro. The Cre-Lox system enables gene expression with exceptional spatial (expresses a gene in specific cells, tissues, or entire organisms) and temporal (at specific time points through the application of the Cre-Lox system) control. Read More ›

In March 2020, Cyagen officially launched the Cyagen Knockout Catalog Models repository – which has provided researchers in the Americas and Europe with ready to use knockout (KO) mouse models in as few as three (3) months. To date, we have cryopreserved sperm from over 10k KO mouse strains to offer affordable, established, and rapidly available KO models to both research institutions and pharmaceutical corporations. Read More ›

The goal of the Taconic-Cyagen Cyagen Animal Model Awards (CAMA) is to support high-value biomedical research projects that utilize mouse or rat. This competition will offer a range of grant awards, collectively valued at over $77,350, that will help fund custom animal model (CAM) projects that will bring the most impact to their respective research fields. Read More ›