Research Trend
RPS23RG1-mediated Stabilization of Synaptic Function Rescues AD-Associated Cognitive Deficits
RPS23RG1-mediated Stabilization of Synaptic Function Rescues AD-Associated Cognitive Deficits
Synaptic impairment is known to be a prerequisite to the cognitive deficiencies exhibited in Alzheimer's Disease (AD), so investigating the mechanisms which
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Latest Discovery
Advancing the Study of Cardiac Chamber Specification During Development & Pathological Remodeling
Advancing the Study of Cardiac Chamber Specification During Development & Pathological Remodeling
Nppa (natriuretic peptide A) is a cardiac hormone that dynamically changes its spatiotemporal expression during heart development.
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Research Trend
The State of Genetically Modified Mouse Models in 2019 – Advances in Human Disease Research
The State of Genetically Modified Mouse Models in 2019 – Advances in Human Disease Research
Genetically engineered animals remain essential for gaining proper understanding of human disease mechanisms and play an important role in a variety of research areas.
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Research Trend
Improving Cancer Models with Humanized Mice
Improving Cancer Models with Humanized Mice
Mouse models have been instrumental in elucidating the pathobiology of cancer formation and inhibition, including that of Colorectal Cancers (CRC) and Prostate Cancers.
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Newsletter
Custom Animal Models for Improving Human Disease Research
Custom Animal Models for Improving Human Disease Research
If your lab is working on research projects that utilize mouse/rat models, off-the-shelf models often come with limitations that may be addressed through genomic modifications to improve homology.
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Research Trend
Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders
Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders
Toll-like receptors (TLRs) are a class of transmembrane proteins that play essential roles in mammalian innate immune responses against infection. In general, TLRs can recognize structurally conserved molecules, collectively referred to
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Research Trend
Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics
Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics
Neurodegenerative diseases have a multitude of factors contributing to their pathogenesis, such as tau accumulation, amyloid-β deposition, and altered network oscillations. Synaptic and neuronal loss are also typical of many of neurodegenerative diseases
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Research Trend
How microRNA may be used to promote heart regeneration
How microRNA may be used to promote heart regeneration
Recent research has aimed to enhance the regeneration capacity of adult cardiomyocytes (CMs), in part by addressing their withdrawal from the cell cycle following myocardial infarction (MI). As a suggested regulator of endogenous CM proliferation
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News
Cyagen Biosciences and Taconic Biosciences Announce Strategic Partnership
Cyagen Biosciences and Taconic Biosciences Announce Strategic Partnership
Rensselaer, NY — July 18, 2018 - Cyagen Biosciences and Taconic Biosciences, global leaders in the generation of custom genetically engineered rodent models and associated services, announced a strategic partnership.
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Research Trend
Treatment and Male-Bias in Autistic Mice
Treatment and Male-Bias in Autistic Mice
Although humans and mice are separated by 100 million years of evolution, mouse and rat models have continually proven themselves as extremely powerful research tools. Many mouse and rat genetic models can even recapitulate complex and...
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