Most Popular
Research Trends
The New Trio in Weight Loss: Mazdutide, Tirzepatide, and Retatrutide — How Much Do You Know About Them?
Jun 12, 2025
Mazdutide is a synthetic peptide analog independently developed by Innovent Biologics. It targets both the GLP-1 (glucagon-like peptide-1) receptor and the GCG (glucagon) receptor, Read More >
Research Trends
New Addition to Ophthalmic Models: Autosomal Recessive Retinitis Pigmentosa (arRP) - Rho KO Mice
Jun 06, 2025
Retinitis Pigmentosa (RP) is a group of inherited retinal degenerative diseases that affect over 1.5 million people worldwide. Read More >
Research Trends
World Thalassemia Day | Powerful Tool for Disease Research: Hbb-bs & Hbb-bt DKO Mouse Models
May 29, 2025
May 8 marks World Thalassemia Day — a timely opportunity to introduce β-thalassemia, a hereditary blood disorder caused by reduced or absent synthesis of the β-globin chains of hemoglobin. Read More >
Research Trends
On Huntington's Disease Awareness Day: How Humanized Models Drive Therapeutic Innovation
May 23, 2025
May 15 marks International Huntington's Disease Awareness Day — a date not only meant to raise public awareness for those affected but also to highlight the urgent need for breakthroughs in treating this devastating condition. Read More >
Research Trends
Gaa Knockout Mice: A Powerful Model for Accelerating Pompe Disease Research
May 15, 2025
Imagine a disease where the very substance meant to fuel your body—glycogen—becomes a silent saboteur, accumulating in critical tissues and gradually stealing a patient's strength and mobility. Read More >
Research Trends
World Lupus Day Spotlight: SLE Animal Models Driving Mechanistic Insights and Therapeutic Innovation
May 09, 2025
Recently, Fate Therapeutics announced that its allogeneic CAR-T cell therapy FT819, developed based on induced pluripotent stem cells (iPSCs), has been granted Regenerative Medicine Advanced Therapy (RMAT) designation by the FDA Read More >
Research Trends
Full-Spectrum SMA Models: Humanized Mice with Varying SMN2 Copy Numbers
Apr 30, 2025
Spinal Muscular Atrophy (SMA) remains one of the most devastating genetic diseases affecting infants and children worldwide. Read More >
Research Trends
Validating GLP-1RA Therapy in Preclinical Mouse Models of Metabolic Dysfunction-Associated Steatohepatitis
Apr 25, 2025
Discover how Cyagen's validated preclinical MASH mouse models are accelerating GLP-1RA therapeutic development through clinically relevant disease modeling and pharmacodynamic evaluation. Read More >
Research Trends
Newsletter
World Hemophilia Day | China Approves First AAV Gene Therapy Drug: How Humanized Animal Models Enable Breakthroughs in Rare Disease Treatment
Apr 17, 2025
On April 10, China’s National Medical Products Administration (NMPA) officially approved Dalnacogene Pankparvovec Injection (brand name: XinJiuning, research code: BBM-H901) Read More >
Research Trends
Preliminary Data: Inducible PKD Mouse Model Shows Phenotype in as Fast as 3 Weeks
Apr 11, 2025
ADPKD is the most common inherited kidney disorder worldwide and a major cause of end-stage kidney disease (ESKD). Read More >