Newsletter
Research Trend
Applications of Sirtuins (SIRT) Knockout Mouse Models in Disease Research
Applications of Sirtuins (SIRT) Knockout Mouse Models in Disease Research
Sirtuins - colloquially known as the longevity genes – are a highly conserved family of NAD1+-dependent enzymes which are involved in the regulation of gene silencing, metabolism, cell division, apoptosis, and genetic material repair. Additionally, it has been reported that sirtuins play important roles in the development of multi-systemic diseases.
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Newsletter
Research Trend
Beyond Mediating Host Cell Entry of SARS-CoV-2: What Roles Does ACE2 Play?
Beyond Mediating Host Cell Entry of SARS-CoV-2: What Roles Does ACE2 Play?
In our fight against the virus and COVID-19, researchers have studied the SARS-CoV-2 virus itself and its host receptor, ACE2, from the aspects of epidemiology, pathology, virus traceability, prevention, and control measures. The human ACE2 receptor is known to interact with SARS-CoV-2 and permit its initial cell entry, making it particularly important to explore its function.
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Newsletter
Virtual Consultations for Custom Animal Model Solutions
Virtual Consultations for Custom Animal Model Solutions
With the emergence of the novel coronavirus (SARS-CoV-2), the meetings, shows, and conferences that allow us to interface with customers in person have been canceled for the foreseeable future. Both the Cyagen US and Taconic Biosciences' Model Design Specialist teams are working remotely from home to help do our part to flatten the curve.
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Newsletter
Research Trend
How to Choose the Right Mouse Models and Genetic Modification Method for Your Research
How to Choose the Right Mouse Models and Genetic Modification Method for Your Research
Our experts put together the following advice on how to choose the most suitable mouse strains & genetic modification techniques for your research. In practical applications, it is necessary to select mouse strain backgrounds that align with your desired research applications to achieve good experimental results.
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Newsletter
Breaking News
Expanded Knockout Catalog Models – Over 10k Genes Now Available
Expanded Knockout Catalog Models – Over 10k Genes Now Available
In our continuing efforts to expand the gene knockout models offered in the Cyagen Knockout Catalog, described in our recent Technical Bulletin, we are proud to announce the availability of over 10,000 KO mouse models.
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Newsletter
ROSA26: The ‘Safe Harbor’ Locus in the Mouse Genome
ROSA26: The ‘Safe Harbor’ Locus in the Mouse Genome
What is the first thing that comes to your mind when we mention ‘safe harbor’? The ‘safe harbor’ we want to talk about today is not the kind for ships, but, rather, the safe locus for targeted integration of exogenous gene in the mouse genome. Let's explore one of the most well-established safe loci in the mouse genome - ROSA26.
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Newsletter
Interview: Impact of COVID-19 Respiratory Illness on the Life Science Research Industry
Interview: Impact of COVID-19 Respiratory Illness on the Life Science Research Industry
With the gradual improvement of the COVID-19 situation in China in the past few days, along with a worsening situation across many regions, research on vaccines and related antiviral drugs has become a key issue for most people both inside and outside the life science research industry.
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Newsletter
Research Trend
Cytokine Storm: The New Perspective for COVID-19 Research
Cytokine Storm: The New Perspective for COVID-19 Research
Since COVID-19 poses a significant threat to public health and also represents a challenge for antiviral drug development and administration globally, current efforts focus on prevention and control while accelerating the research on the SARS-CoV-2 coronavirus, which has caused the outbreak of COVID-19.
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Newsletter
CRISPR/Cas9 Versus ES Cell Targeting：Which is the Optimal Solution?
CRISPR/Cas9 Versus ES Cell Targeting：Which is the Optimal Solution?
With the rapid advancement of biomedical technology in recent years, customized treatment methods such as targeted medicine, immunotherapy, and gene therapy have become the main directions of biomedical innovation - which is intimately related to the development of gene-editing technology.
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Newsletter
BALB/c Strains Now Available for TurboKnockout® Embryonic Stem Cell (ESC) Mediated Services
BALB/c Strains Now Available for TurboKnockout® Embryonic Stem Cell (ESC) Mediated Services
Cyagen is proud to announce the availability of BALB/c mouse models for all embryonic stem cell (ESC) based gene targeting services, including our proprietary TurboKnockout® technology.
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