Custom Animal Models for Improving Human Disease Research
Newsletter
Custom Animal Models for Improving Human Disease Research
If your lab is working on research projects that utilize mouse/rat models, off-the-shelf models often come with limitations that may be addressed through genomic modifications to improve homology. Read More ›
Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders
Research Trend
Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders
Toll-like receptors (TLRs) are a class of transmembrane proteins that play essential roles in mammalian innate immune responses against infection. In general, TLRs can recognize structurally conserved molecules, collectively referred to Read More ›
Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics
Research Trend
Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics
Neurodegenerative diseases have a multitude of factors contributing to their pathogenesis, such as tau accumulation, amyloid-β deposition, and altered network oscillations. Synaptic and neuronal loss are also typical of many of neurodegenerative diseases Read More ›
How microRNA may be used to promote heart regeneration
Research Trend
How microRNA may be used to promote heart regeneration
Recent research has aimed to enhance the regeneration capacity of adult cardiomyocytes (CMs), in part by addressing their withdrawal from the cell cycle following myocardial infarction (MI). As a suggested regulator of endogenous CM proliferation Read More ›
Cyagen Biosciences and Taconic Biosciences Announce Strategic Partnership
News
Cyagen Biosciences and Taconic Biosciences Announce Strategic Partnership
Rensselaer, NY — July 18, 2018 - Cyagen Biosciences and Taconic Biosciences, global leaders in the generation of custom genetically engineered rodent models and associated services, announced a strategic partnership. Read More ›
Treatment and Male-Bias in Autistic Mice
Research Trend
Treatment and Male-Bias in Autistic Mice
Although humans and mice are separated by 100 million years of evolution, mouse and rat models have continually proven themselves as extremely powerful research tools. Many mouse and rat genetic models can even recapitulate complex and... Read More ›
Metastasis triggered by macrophage cytoplasm
Latest Discovery
Metastasis triggered by macrophage cytoplasm
Macrophages are the first line of defense against infections, playing important roles in consuming pathogens and in regulating inflammation. In general, these functions help maintain a healthy organism, keeping infections at bay and promoting... Read More ›
Anorexic mice
Latest Discovery
Anorexic mice
During the past several years, there has been an increasing public awareness of mental illness and their societal and health consequences. Eating disorders represent one of the most damaging groups of mental illnesses. Current estimates are... Read More ›
'Trimming the fat' with CRISPR
Latest Discovery
'Trimming the fat' with CRISPR
Around 20 million years ago, for unknown reasons, wild pigs lost an important metabolic gene known as uncoupling protein 1 (UCP1). In most mammals this gene plays a major role in generating body heat for thermoregulation by burning fat... Read More ›
A mammalian half-day clock
Latest Discovery
A mammalian half-day clock
Last month, the Nobel Foundation recognized Jeffrey Hall, Michael Rosbash, and Michael Young "for their discoveries of molecular mechanisms controlling the circadian rhythm". This 24-hour "clock" influences many physiological processes... Read More ›

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