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White Paper
Gene Therapy Studies and Humanized Mouse Models of Genetic Diseases
Aug 24, 2021
The completion of the rat and mouse gene sequencing draft was an important milestone after the human genome draft sequence - as it initiated the rapid advancement of these murine models in the research of human genes and genetic illnesses. Read More >
Newsletter
Video
How to Search the Cyagen Knockout Catalog Models Resource
Aug 12, 2021
Researchers may search for their desired gene KO and/or cKO model using either the website search bar, as shown in the video below, or by using our dedicated repository search page. Read More >
Weekly Gene
Indispensable Genes for Lymphoid Cell V(D)J recombination & Immunotherapy - RAG1 & RAG2
Aug 11, 2021
The recombination-activating genes, Read More >
Newsletter
Choosing a Transfection Method to Improve Knockout Cell Line Generation Efficiency
Aug 05, 2021
when using the CRISPR-Cas9 strategy in the construction of gene knockout (KO) cell lines, researchers might be troubled about choosing the specific model generation method from plasmid-based, viral delivery, and ribonucleoprotein (RNP) transfection. Read More >
Newsletter
FAQ: Cell Line Verification
Jul 30, 2021
Cell lines verification is of the utmost importance. Skipping the verification step can lead to invalid research data, leading to lost time and money and retractions of publication. Herein, we have collected the Frequently Asked Questions on cell lines verification, hoping to provide research tips on cell line verification. Read More >
Newsletter
FAQ: Knockout Cell Line Generation
Jul 30, 2021
Gene knockout (KO) cell lines enable researchers to study the role of specific genes by comparing the phenotypic differences among the knockout and wildtype cells. Herein, we have collected the Frequently Asked Questions on knockout cell line generation, hoping to help researchers gain a proper understanding of how knockout cell lines are developed and used. Read More >
Weekly Gene
【Gene of the Week】Popular Gene Target of Lung Cancer Research – MET
Jul 28, 2021
The MET (Mesenchymal Epithelial Transition) gene encodes a prototypical receptor tyrosine kinase, which is involved in the tyrosine kinase signaling pathway that regulates cell motility, survival, proliferation, invasion, and metastasis in many cancers. Read More >
Newsletter
FAQ: Cell Line Generation Basics
Jul 27, 2021
It is well known that cell lines play an important role in gene function studies, drug screening, and the production of recombinant proteins and antibodies. Herein, we have collected the Frequently Asked Questions on cell line generation, hoping to help researchers gain a proper understanding of how cell lines are developed and used. Read More >
Newsletter
How to Find the Best Immunodeficient Mice Model for Your Research?
Jul 27, 2021
The lack of appropriate animal models often limits the study of human pathologies. Infectious diseases in humans are primarily studied using mice. However, many human-specific infectious agents do not affect mice. Immune-deficient laboratory mice are genetically engineered to express human genes or transplanted with human tissues or stem cells. Human genes, organs, pathologies, and drugs intended for human use can be studied using these mice. Read More >
Newsletter
Comprehensive Introduction of Apoe Knockout Mice
Jul 02, 2021
Apoe knockout mice can be used to study the function of APOE in lipid metabolism, atherosclerosis, and nerve damage; It also helps to study interventional therapies that can change the atherosclerotic process. Read More >