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Research Trends
B6-Igl Knockout Mice: Research Model for B Cell Development & Antibody Diversity
Oct 31, 2024
The novel B6-Igl Knockout (KO) mouse model exclusively expresses κ light chain immunoglobulins, offering researchers a powerful tool for exploring B cell development and antibody diversity. Read More >
Research Trends
USH2A Humanized Disease Model for Usher Syndrome Type II Research
Oct 25, 2024
Usher Syndrome (USH) is a genetic disorder that causes both hearing and vision loss due to mutations in genes which play a critical role in inner ear and retinal function. Read More >
Research Trends
Familial Dysautonomia (FD) Humanized Disease Models: ELP1 & ELP1 IVS20+6T>C
Oct 18, 2024
With the advancement of whole-genome sequencing, it has become increasingly recognized that intronic mutations play a significant role in various diseases, particularly rare diseases. Read More >
Research Trends
Hep G2 Cell Line: Liver Cancer Research Applications with Gene Editing & CDX Tumor Models
Oct 10, 2024
Explore Hep G2 cell line applications in liver cancer research, gene editing using Smart-CRISPR™, and subcutaneous xenograft (CDX) tumor models. Discover best practices for cell culture, gene editing services, and tumor modeling. Read More >
Research Trends
HSD17B13 Humanized Mouse Model: A Breakthrough Tool for MASLD and RNAi Therapy Research
Sep 27, 2024
Metabolic dysfunction-associated steatotic liver disease (MASLD) is a complex, multifactorial condition that has become a leading cause of liver-related morbidity and mortality. Read More >
Research Trends
How the B6-hTGFBI Humanized Mouse Model is Advancing Corneal Dystrophy Research
Sep 23, 2024
Corneal dystrophy (CD) is a group of rare hereditary disorders caused by abnormal deposits of substances in the cornea. Read More >
Research Trends
Unveiling the Secrets of the DIO-B6-M Mouse Model for Obesity Research
Sep 13, 2024
Obesity has become a global health issue. According to statistics, 2.5 billion adults were classified as overweight in 2022, with over 890 million suffering from obesity. Read More >
Research Trends
How to Culture & Edit NCI-H358 Cells: Best Practices for KRAS G12C Mutation Research
Sep 05, 2024
Lung cancer researchers often utilize the NCI-H358 cell line for its KRAS G12C mutation to test inhibitors specifically targeting this mutation, as well as explore potential combination therapy strategies. Read More >
Research Trends
Research Notes: How to Perform Successful Gene Editing & Cell Culturing with SH-SY5Y Cells
Aug 23, 2024
The SH-SY5Y cell line is one of the most widely used cell models for studying neurodegenerative diseases. In this post, we provide details on how to utilize the SH-SY5Y cell line for research purposes, including protocols for successful gene editing and cell culture. Read More >
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FAQ: Advanced Antibody Development with Cyagen HUGO-Ab & Biointron AbDrop
Aug 12, 2024
Cyagen's HUGO-Ab platform utilizes fully humanized mice engineered to produce human monoclonal antibodies. Read More >