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Newsletter
Myriad of CRISPR Research Model Services
May 27, 2021
If your lab is utilizing CRISPR in animal or in-vitro modeling work, we have a wide variety of CRISPR offerings with great discounts. Read More >
Newsletter
Announcement - Introducing Cyagen Upgraded Animal Supporting Services
May 27, 2021
yagen aims to support biomedical research with our expertise. We are committed to enabling development of precise animal models to help researchers study disease mechanisms, target validation, drug screening and more. Our comprehensive services cover the entire process of animal model generation - from gene targeting strategy design and animal model development, through to breeding and animal phenotype analysis – to accelerate your scientific research progress. Read More >
Newsletter
What Are Transgenic Rats
May 27, 2021
Transgenic rats are animal models which have foreign DNA incorporated into the rat genome and are used to research a wide range of gene functions and human diseases. Read More >
Newsletter
How to Effectively Generate CRISPR Gene Knockout Cell Lines? Choosing a Transfection Method
May 25, 2021
After deciding upon a CRISPR-mediated gene knockout strategy and obtaining the gRNA, the next step would be choosing the suitable strategy for cell transfection to introduce gRNA and Cas9 protein into cells. The efficiency of this transfection step directly affects the overall success rate of CRISPR/Cas-mediated gene editing and subsequent model generation. Read More >
Newsletter
Advancing Research with Humanized Mouse Models
May 20, 2021
A humanized mouse model is a broad term referring to a mouse engrafted with functional human genes, cells, or tissues. This type of model is usually used as an powerful in vivo model for preclinical study of human diseases. Humanized mouse models have become an important animal model for identifying how human genes impact development and disease. Read More >
Newsletter
What is a Knockin Mouse?
May 20, 2021
Gene knock-in (KI), a.k.a. knockin, mice are generated by introducing specific mutations or exogenous genes into specific sites of the target gene through homologous recombination, so that the expression of the gene knockin may be tracked through the expression of a reporter. Read More >
Newsletter
Animal Models for Metabolic Disease Research
May 20, 2021
Animal Models for Metabolic Disease Read More >
Newsletter
How to Choose the Best Knockout Cell Line Strategy
May 18, 2021
The traditional approaches used in gene function studies, especially in cell lines, include gene interference, gene overexpression, and gene knockout. Herein, we will focus on discussing the most popular approach, gene knockout – a mutation that inactivates a gene function. Read More >
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Using CRISPR to Develop Knockout Mouse Models for Research
May 17, 2021
Engineered nuclease-mediated genome editing, especially CRISPR, has emerged as a promising technology which can serve as an alternative to the conventional, embryonic stem (ES) cell homologous recombination-based generation of animal models. Read More >
Newsletter
Breaking News
Taconic-Cyagen Custom Animal Model Awards (CAMA) Announces 6 Winners
May 14, 2021
We are delighted to announce the winners of the first Taconic-Cyagen Custom Animal Model Awards (CAMA) competition. Read More >