Research Trend
The State of Genetically Modified Mouse Models in 2019 – Advances in Human Disease Research
Genetically engineered animals remain essential for gaining proper understanding of human disease mechanisms and play an important role in a variety of research areas. Read More ›
Research Trend
Improving Cancer Models with Humanized Mice
Mouse models have been instrumental in elucidating the pathobiology of cancer formation and inhibition, including that of Colorectal Cancers (CRC) and Prostate Cancers. Read More ›
Newsletter
Custom Animal Models for Improving Human Disease Research
If your lab is working on research projects that utilize mouse/rat models, off-the-shelf models often come with limitations that may be addressed through genomic modifications to improve homology. Read More ›
Research Trend
Application of Toll-Like Receptors (TLRs) Animal Models in Cancer and Autoimmune Disorders
Toll-like receptors (TLRs) are a class of transmembrane proteins that play essential roles in mammalian innate immune responses against infection. In general, TLRs can recognize structurally conserved molecules, collectively referred to Read More ›
Research Trend
Custom Animal Models of Neurodegeneration for Investigation of Potential Therapeutics
Neurodegenerative diseases have a multitude of factors contributing to their pathogenesis, such as tau accumulation, amyloid-β deposition, and altered network oscillations. Synaptic and neuronal loss are also typical of many of neurodegenerative diseases Read More ›
Research Trend
How microRNA may be used to promote heart regeneration
Recent research has aimed to enhance the regeneration capacity of adult cardiomyocytes (CMs), in part by addressing their withdrawal from the cell cycle following myocardial infarction (MI). As a suggested regulator of endogenous CM proliferation Read More ›
News
Cyagen Biosciences and Taconic Biosciences Announce Strategic Partnership
Rensselaer, NY — July 18, 2018 - Cyagen Biosciences and Taconic Biosciences, global leaders in the generation of custom genetically engineered rodent models and associated services, announced a strategic partnership. Read More ›
Research Trend
Treatment and Male-Bias in Autistic Mice
Although humans and mice are separated by 100 million years of evolution, mouse and rat models have continually proven themselves as extremely powerful research tools. Many mouse and rat genetic models can even recapitulate complex and... Read More ›
Latest Discovery
Metastasis triggered by macrophage cytoplasm
Macrophages are the first line of defense against infections, playing important roles in consuming pathogens and in regulating inflammation. In general, these functions help maintain a healthy organism, keeping infections at bay and promoting... Read More ›
Latest Discovery
Anorexic mice
During the past several years, there has been an increasing public awareness of mental illness and their societal and health consequences. Eating disorders represent one of the most damaging groups of mental illnesses. Current estimates are... Read More ›
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