Most Popular
May 13, 2021
The Taconic-Cyagen Alliance (The Alliance) has capabilities to ensure the success of any project. The Alliance provides specially-tailored products and services for the academic and non-profit markets. Together, we have streamlined the model design process to provide the academic market access to premium model generation and colony management services backed by comprehensive capabilities and cutting-edge, fully licensed technologies with competitive pricing. As partners, Taconic and Cyagen leverage the power of our complementary approaches to provide customers with the best and most competitive solutions for their projects. Read More >
Latest Discovery
Research Trend
LARP7-Mediated U6 snRNA Modification and Its Role in Pre-mRNA Splicing As Well As Its Functions in Mouse Spermatogenesis
May 11, 2021
In higher eukaryotes, most genes co Read More >
Research Trend
Research Process of Parkinson’s Disease
May 10, 2021
PD ranks second among neurodegenerative diseases. The most well-known symptom of PD is involuntary tremors, characterized by uncontrolled shaking, most notably in the hands. Another important symptom is the weakening of balance ability, but it should be noted that the weakening of balance has nothing to do with cerebellar injury. Read More >
Cyagen Knockout Catalog Model Resource - Improve Your Research Efficiency
May 06, 2021
With continuous advancement, our se Read More >
Research Trend
Cyagen Conditional Knockout Mouse Model Publication Alert
Apr 29, 2021
The following publications demonstrate the use of conditional knockout mouse models across a range of human disease research fields, including immunology, cardiology, metabolomics, oncology and more. Read More >
Research Trends
Case Study
Research Process of Alzheimer Disease
Apr 28, 2021
Alzheimer’s disease (AD) maintains the highest prevalence and morbidity among neurodegenerative diseases. Memory loss is the key symptom of AD, the aggravation of which will lead to other symptoms associated with the disease development, and eventually lead to death of the patients. AD brings suffering to the patients and their families - a heavy burden on society. Read More >
Research Trend
Conditional Knockout (cKO) Mice - Powerful Tool for Understanding Disease Mechanisms
Apr 26, 2021
Conditional knockout (cKO) mice can be used to study specific gene functions and related human diseases. Compared with traditional knockout (KO) mice, conditional knockout mice are obtained with a gene that deleted only in specific tissues or on an inducible basis. Compared with constitutively expressed gene mutations, conditional models provide greater temporal and regional control of gene expression – often serving as a more accurate model for studying human diseases. Read More >
Weekly Gene
LRRK2: A Pathogenic Gene of Parkinson's Disease (PD)
Apr 23, 2021
Parkinson's Disease (PD) is a neurodegenerative disease that cannot be cured. In this article, we review the background information, research insights and applications on LRRK2, a pathogenic gene of PD, providing useful information for further scientific innovation. Read More >
Weekly Gene
PRKN: A Pathogenic Gene of Parkinson's Disease (PD)
Apr 22, 2021
Parkinson's disease (PD) is a neurodegenerative disorder that affects behavior and motor skills. In this article, we review the background information, research insights, and applications related to PRKN, a pathogenic gene of PD. Read More >
Research Trend
Alzheimer's Disease Research Resources List
Apr 21, 2021
Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder, which affects 20 to 30 million individuals worldwide. Currently, no effective therapies to treat or cure this disease have been developed. Read More >