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Weekly Gene
A Gene Related to Excitement- GRIA3
Nov 09, 2021
This week’s subject is the Glutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) gene, which is closely related to the feeling of excitement. Read More >
Weekly Gene
NLRP3 and Familial Cold Autoinflammatory Syndrome
Nov 02, 2021
The NLRP3 gene encodes NLR Family Pyrin Domain Containing 3 - a pyrin-like protein which contains a pyrin domain, a nucleotide binding site (NBS) domain, and a leucine-rich repeat sequence (LRR) motif. Read More >
Weekly Gene
An Important Target of the Deadly Lung Disease Idiopathic Pulmonary Fibrosis—CAV1
Oct 26, 2021
The CAV1 gene is responsible for encoding the Caveolin 1 (CAV1) protein, also called caveolin-1 (CAV-1), which belongs to the Caveolin family of integral membrane proteins. Read More >
Weekly Gene
Cockayne Syndrome B (CSB) and ERCC6 Gene
Oct 19, 2021
Mutations in the excision and repair of cross-complementation group 6 (ERCC6) gene is known to result in Cockayne syndrome B (CSB), among some other disorders. Read More >
White Paper
White Paper: Gene Therapy Research and Humanized Mouse Models
Sep 26, 2021
In Cyagen's exclusive White Paper, our experts briefly introduce the background of gene therapy for rare diseases and explore the applications of humanized mouse models for genetic diseases. Read More >
How to Search the Cyagen Knockout Catalog Models Resource
Aug 12, 2021
Researchers may search for their desired gene KO and/or cKO model using either the website search bar, as shown in the video below, or by using our dedicated repository search page. Read More >
Weekly Gene
Indispensable Genes for Lymphoid Cell V(D)J recombination & Immunotherapy - RAG1 & RAG2
Aug 11, 2021
The recombination-activating genes, Read More >
Choosing a Transfection Method to Improve Knockout Cell Line Generation Efficiency
Aug 05, 2021
when using the CRISPR-Cas9 strategy in the construction of gene knockout (KO) cell lines, researchers might be troubled about choosing the specific model generation method from plasmid-based, viral delivery, and ribonucleoprotein (RNP) transfection. Read More >
FAQ: Cell Line Verification
Jul 30, 2021
Cell lines verification is of the utmost importance. Skipping the verification step can lead to invalid research data, leading to lost time and money and retractions of publication. Herein, we have collected the Frequently Asked Questions on cell lines verification, hoping to provide research tips on cell line verification. Read More >
FAQ: Knockout Cell Line Generation
Jul 30, 2021
Gene knockout (KO) cell lines enable researchers to study the role of specific genes by comparing the phenotypic differences among the knockout and wildtype cells. Herein, we have collected the Frequently Asked Questions on knockout cell line generation, hoping to help researchers gain a proper understanding of how knockout cell lines are developed and used. Read More >