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Research Trends
How the B6-hTGFBI Humanized Mouse Model is Advancing Corneal Dystrophy Research
Sep 23, 2024
Corneal dystrophy (CD) is a group of rare hereditary disorders caused by abnormal deposits of substances in the cornea. Read More >
Research Trends
Unveiling the Secrets of the DIO-B6-M Mouse Model for Obesity Research
Sep 13, 2024
Obesity has become a global health issue. According to statistics, 2.5 billion adults were classified as overweight in 2022, with over 890 million suffering from obesity. Read More >
Research Trends
How to Culture & Edit NCI-H358 Cells: Best Practices for KRAS G12C Mutation Research
Sep 05, 2024
Lung cancer researchers often utilize the NCI-H358 cell line for its KRAS G12C mutation to test inhibitors specifically targeting this mutation, as well as explore potential combination therapy strategies. Read More >
Research Trends
Research Notes: How to Perform Successful Gene Editing & Cell Culturing with SH-SY5Y Cells
Aug 23, 2024
The SH-SY5Y cell line is one of the most widely used cell models for studying neurodegenerative diseases. In this post, we provide details on how to utilize the SH-SY5Y cell line for research purposes, including protocols for successful gene editing and cell culture. Read More >
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FAQ: Advanced Antibody Development with Cyagen HUGO-Ab & Biointron AbDrop
Aug 12, 2024
Cyagen's HUGO-Ab platform utilizes fully humanized mice engineered to produce human monoclonal antibodies. Read More >
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Breaking News
Cyagen's Partner InnoVec Receives US FDA Investigational New Drug Approval for IVB103 Clinical Trials
Aug 09, 2024
On July 26, 2024, InnoVec's IVB103 injection received early Investigational New Drug (IND) approval from the U.S. Food and Drug Administration (FDA), which may now proceed to the clinical trial phase. Read More >
Research Trends
Adipoq-iCre Mice for Conditional Gene Targeting of Adipose Tissues & Fluorescent Detection Data
Aug 02, 2024
In the realm of scientific research, particularly in studies focusing on fat cells and metabolic diseases, accurate and efficient fluorescent detection is essential. Read More >
Research Trends
Improving Pancreas-Specific Cre Mouse Lines with the Pdx1-CreERT2 Mouse Model
Jul 29, 2024
The Cre-Lox system allows for gene knockout/knockin in specific cells/tissues, with the timing of its expression is determined by the promoter. Read More >
Research Trends
Humanized Immune System Mice: An Effective Preclinical Model for Reproducing Human Immune-Tumor Interactions
Jul 19, 2024
Humanized Immune System Mice (HIS mice) are developed by transplanting human immune system components into mice, resulting in animal models that partially or fully replicate human immune system functions. Read More >
Research Trends
Highly Efficient Human NK Cell Immune Reconstitution Mouse Models: NKG-hIL15 & huHSC-NKG-hIL15 Mice
Jul 12, 2024
Immunotherapy works by mobilizing immune cells within the body to enhance the immune system's ability to recognize, kill, and eliminate tumor cells. Given the differences between the immune systems of mice and humans, immunotherapies are typically evaluated in preclinical studies using humanized immune system (HIS) mouse models. Read More >