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Research Trends
Applications of iPSC-based Disease Models
Feb 16, 2023
Induced pluripotent stem cells (iPSCs) provide an ideal in vitro platform for studying disease mechanisms and developing cell therapy approaches, as they can be derived from cells with a singular genetic background and tailored to replicate specific disease phenotypes. Read More >
Research Trends
What is Autism Spectrum Disorder (ASD) and what are the gene-edited mouse models for autism?
Jan 29, 2023
Autism Spectrum Disorder (ASD) refers to a broad range of complex neurodevelopmental conditions that has many theorized causative factors, but there have been many genetic mutations associated with susceptibility to autism and altered brain structure associated with ASD. Read More >
Research Trends
How Much Do You Know About The Behavioral Differences Between Rats And Mice?
Jan 16, 2023
Murine genomes share great similarity with the human genome, which has made both mice and rats fantastic models for a wide range human disease research. Read More >
Research Trends
The Morris Water Maze: Illustrated Handbook for Researchers
Jan 10, 2023
The Morris water maze is a widely used task in behavioral neuroscience for the study of spatial learning and memory, while additionally testing endurance and physical strength. Read More >
Research Trends
Y Maze Behavioral Task: Studying the function of spatial learning and memory in Neuroscience research
Dec 29, 2022
Since animals can't speak, they can't tell you whether they remember what just happened, or what they are experiencing at this moment. The most direct way to understand what they are thinking is to observe their behaviors. Read More >
Research Trends
A Good Helper for SARS-CoV-2 & COVID-19 Research: Selection and Application of Mouse Models
Dec 06, 2022
Animal models have assisted researchers' understanding of COVID-19 pathogenesis and host immune response to SARS-CoV-2 infection, and are of great significance in helping the rapid development of disease preventatives, vaccines, and treatments. Read More >
Research Trends
Application of Flow Cytometry in Preclinical CAR-T Development
Nov 28, 2022
Chimeric Antigen Receptor T-Cell (CAR-T) Immunotherapy uses genetic engineering technology to transform autologous or allogeneic T cells into new killer cells targeting tumor-specific antigens, by which remarkable results have been achieved in the treatment of hematological malignancies. Read More >
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Animal Welfare Focus: Humane Endpoints in Rats and Mice in Tumor Research Programs
Nov 04, 2022
In recent years, more and more people advocate the "3Rs" principle of experimental animals: Reduction, Replacement, and Refinement. Read More >
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Vision Stolen by Years - Age-related Macular Degeneration
Oct 26, 2022
Many older adults experience a noticeable loss of vision as age increases, but the inability to see fine details in the center of vision may be a sign of age-related macular degeneration (AMD). Read More >
Research Trends
Accelerating CAR-T Cell Therapy Research
Oct 13, 2022
By using the body's own immune system to kill tumor cells, immune cell therapy is anticipated to be a breakthrough strategy to "cure" many types of cancer. Among them, chimeric antigen receptor T-cell immunotherapy (CAR-T) has achieved remarkable results in the treatment of various hematological malignancies. As of 2022, seven CAR-T cell therapy products have been launched globally, including three in China. Read More >