Are you considering custom animal models to accelerate your next research project? Cyagen's Discount of the Decade Event can help you extend your research with big savings for multiple projects - the more animal models you order from any eligible service, the more you save!

Until December 31st, we are offering large discounts on orders of custom mouse and rat model generation projects. Collaborate with your colleagues to order at least 4 projects and enjoy discounts up to 25% OFF – over $31,550 in savings on TurboKnockout® conditional knockout/knockin mice.

Cyagen’s proprietary TurboKnockout® technology provides rapid turnaround time for conditional models – up to 6 months faster than traditional ES cell targeting methods – while also enabling Large Fragment Knock-Ins (LFKIs) up to 200 kb.

Comparison of Gene Targeting Methods:

Features TurboKnockout® Traditional Gene Targeting CRISPR/Cas9
Turnaround 6-8 months 10-14 months 5-9 months
Methodology Established 2015 1998 2013
Approach Homologous recombination in ES cell by Cyagen TurboKnockout® technology Homologous recombination in ES cell by traditional technology CRISPR/Cas9 nuclease mediated gene targeting by pronuclear injection
Applications Conditional knockout
Large fragment knockin
Conditional knockout
Large fragment knockin
Global knockout
Point mutation
Short fragment knockin
Innovative self-deleting selection cassette Yes --- ---
Potential off-site target effects No No Yes
Ability to introduce large fragment Yes Yes Limited
Germline guarantee Yes Yes Yes


In addition to the cost savings, Cyagen is the world's leading provider of custom mouse models offering a full guarantee and 24-hour technical support throughout your project, even after delivery of your animals. Since our founding in 2005, Cyagen has been cited in over 2,800 publications. With over 53 citations in 2019 and counting, our model generation services continue to provide unmatched economy, process ease, and efficiency: allowing you to get back to discovery.

Start 2020 with peace of mind - Cyagen's experts have generated thousands of models and offer 100% money back guarantee. We can initiate model generation projects immediately or provide models based on your research timeline.

Act now to lock-in these savings – contact us to request a free project strategy & quote for your next study before the Discount of the Decade ends on December 31, 2019!