NKG B2m KO
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Strain Description
NKG B2m KO mice are constructed by knocking out the B2m gene on the background of NKG mice. Compared with NKG mice, NKG B2m KO mice have a significantly longer survival period after PBMC transplantation and can be used for long-term studies of PBMC immune system reconstitution.
Application Area
Establishment of humanized immune system mouse model
Research on graft-versus-host disease (GvHD)
Research on the immune system, hematopoietic system, and blood disease
Cell line-derived xenograft (CDX) and drug screening and efficacy evaluation
Patient-derived xenograft (PDX) and drug screening and efficacy evaluation
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