Drug Evaluation Animal Models

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Animal models of disease are an indispensable tool to study the mechanisms of human disease development, as well as for drug screening and efficacy evaluations. Accurate disease animal models can accelerate the development of new drugs. To provide the highest-quality models to researchers, Cyagen continuously optimizes our gene editing technologies and recruits leading specialists to support your scientific innovation. Cyagen has established an animal platform for drug development, screening, or evaluation covering a wide range of disease studies, including cancer, immunity, endocrine, cardiovascular, neurological, and infectious diseases.

Cyagen can provide you with a variety of drug evaluation models along with phenotype analysis services – delivering reliable and expedient data reporting for your project.

 

Metabolic Disease Models

With the aging of society and the prevalence of obesity, the incidence rate of metabolic diseases is increasing, which has posted a serious threat to human health. The most common metabolic diseases include obesity, type 2 diabetes mellitus due to insulin resistance and nonalcoholic fatty liver disease / nonalcoholic fatty hepatitis (nafld/nash).

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Tumor Model

Mouse tumor model is an indispensable tool for studying tumor development mechanism, drug screening and efficacy evaluation. Cyagen animal model platform for innovative drug research and development can provide various accurate tumor models, tumor cell line transplantation model and human tumor xenotransplantation model (CDX) according to your research needs. We can develop all kinds of subcutaneous, in situ or metastatic tumor models, and provide highly customized pharmacodynamic services for the corresponding models to meet your research needs.

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Immunodeficient Mice

Immunodeficient mice refer to the mice with defects or deletions of one or more immune components (B cells, T cells, NK cells, etc.) in the immune system caused by congenital genetic mutation or artificial methods. They play an increasingly important role in the research of immunity, tumor, stem cell and the treatment of infectious diseases. Congenital immunodeficiency mice are more commonly used in scientific research experiments, which are genetically deficient, such as nude mice, nod SCID and so on, and are often used as tumor model experimental animals. Severe immunodeficiency mice are widely used in the construction of humanized mice due to the lack of T, B and NK immune cells.

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