B6-hMECP2
Product Type
Age
Genotype
Sex
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Basic Information
Model Name
B6-hMECP2
Product ID
C001568
Gene Name
Background
C57BL/6NCya
Gene Alias
RS; RTS; RTT; PPMX; MRX16; MRX79; MRXSL; AUTSX3; MRXS13
Classification
Full-Gene Humanized Models,Neurological Disease Models
NCBI ID
Phenotype
Chromosome
X
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Note: When using this mouse strain in a publication, please cite “B6-hMECP2 mice (Catalog C001568) were purchased from Cyagen.”
Strain Description
This strain is a humanized MECP2 gene mouse model that can be used for RTT research. Homozygous B6-hMECP2 mice are viable and fertile. Additionally, based on the independently developed TurboKnockout fusion BAC recombination technology, Cyagen can also generate hot mutation models based on this strain (B6-hMECP2*T158M, Catalog Number: C001569) and provide customized services for specific mutations to meet experimental needs in pharmacology and other RTT-related fields.
Application Area
Research on Rett syndrome (RTT)
Validation Data