hPdcd1 (hPD-1)
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
hPdcd1 (hPD-1)
Product ID
C001524
Gene Name
Background
C57BL/6JCya
Gene Alias
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
Classification
Tumor Target Humanized Models,Immune Target Humanized Models
NCBI ID
Phenotype
Chromosome
2
Document
Note: When using this mouse strain in a publication, please cite “hPdcd1 (hPD-1) mice (Catalog C001524) were purchased from Cyagen.”
Strain Description
This strain is a genetically modified mouse model in which the gene encoding the mouse PD-1 protein is humanized, resulting in the expression of human PD-1 protein in mice. This model can be used for research in drug development, efficacy and safety evaluation, tumor immunotherapy evaluation, and immune system mechanisms related to PD-1.
Application Area
Development and screening of PD-1-targeted drugs
Efficacy and safety evaluation of PD-1-targeted drugs
Evaluation of tumor immunotherapy
Research on the immune system and tumor immune escape mechanisms
Validation Data
References