Atp7b KO
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Strain Description
This strain is an Atp7b deletion mouse model, which uses gene editing technology to knock out Atp7b, the homolog of the human ATP7B gene in mice that lack the expression of ATP7B protein and can be used in the study of disorders related to copper metabolisms such as Wilson's disease, acute liver failure, and steatohepatitis. The heterozygous Atp7b KO mice are viable and fertile, and homozygous mice have a reduced life expectancy.
Application Area
Copper Metabolism Research
Wilson’s Disease Research
Acute Liver Failure Research
Steatohepatitis Research
Other Research Related to Copper Metabolism Disorders
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