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Uox KO
Product ID:
C001232
Background:
C57BL/6JCya
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Strain Description
This strain is a uricase-deficient mouse line generated by knocking out the mouse Uox gene. Due to impaired uricase synthesis, these mice spontaneously exhibit a hyperuricemic phenotype. Heterozygous Uox KO mice are viable and fertile. Homozygous Uox KO mice require allopurinol or similar drugs for postnatal survival.
Application Area
Area
Hyperuricemia Research
Area
Gout and Related Disease Research
Area
Other Metabolic and Renal Disease Research
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