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B6-hGDF15
Product ID:
C001520
Background:
C57BL/6JCya
Documents:
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Strain Description
This strain is a mouse Gdf15 gene humanized model expressing human GDF15 protein obtained by replacing the sequence encoding the endogenous structural domain in the mouse Gdf15 gene with the sequence encoding the structural domain in the human GDF15 gene. B6-hGDF15 mice can be used for research on metabolic diseases, cardiovascular diseases, tumor occurrence and development, etc., to assist in the preclinical evaluation of GDF15-targeted drugs.
Application Area
Area
Research on cardiovascular diseases such as heart disease
Area
Research on metabolic diseases such as diabetes and anorexia
Area
Research on colorectal cancer, prostate cancer, and other cancers
Area
Preclinical evaluation of GDF15-targeted drugs
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