B6-hTFRC/hDMD (E44-45)
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Strain Description
The B6-hTFRC/hDMD (E44-45) mouse model, generated by mating B6-hTFRC (CDS) mice (Catalog Number: C001584) with B6-hDMD (E44-45) mice (Catalog Number: I001204), is a humanized model. It can be used for research on iron metabolism disorders, Duchenne muscular dystrophy (DMD), neurodegenerative diseases, and tumorigenesis, assisting in the development of TFRC/DMD-targeted drugs and preclinical pharmacological and efficacy evaluations.
Application Area
Research on iron metabolism disorders, Duchenne Muscular Dystrophy (DMD), neurodegenerative diseases, and tumor development
Development, screening, and efficacy evaluation of TFRC/DMD-targeted therapies
Research and evaluation of drug delivery across the blood-brain barrier (BBB)
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