B6-hTFRC/hDMD (E44-45)
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Model Name
B6-hTFRC/hDMD (E44-45)
Product ID
C001597
Background
C57BL/6NCya
Gene Alias
BMD; CMD3B; MRX85; DXS142; DXS164; DXS206; DXS230; DXS239; DXS268; DXS269; DXS270; DXS272; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Classification
Full-Gene Humanized Models,Neurological Disease Models
Chromosome
X
Document
Note: When using this mouse strain in a publication, please cite “B6-hTFRC/hDMD (E44-45) mice (Catalog C001597) were purchased from Cyagen.”
Strain Description
The B6-hTFRC/hDMD (E44-45) mouse model, generated by mating B6-hTFRC (CDS) mice (Catalog Number: C001584) with B6-hDMD (E44-45) mice (Catalog Number: I001204), is a humanized model. It can be used for research on iron metabolism disorders, Duchenne muscular dystrophy (DMD), neurodegenerative diseases, and tumorigenesis, assisting in the development of TFRC/DMD-targeted drugs and preclinical pharmacological and efficacy evaluations.
Application Area
Research on iron metabolism disorders, Duchenne Muscular Dystrophy (DMD), neurodegenerative diseases, and tumor development
Development, screening, and efficacy evaluation of TFRC/DMD-targeted therapies
Research and evaluation of drug delivery across the blood-brain barrier (BBB)
Validation Data