B6-hPD-1/hVEGFA
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
B6-hPD-1/hVEGFA
Product ID
C001598
Background
C57BL/6JCya
Gene Alias
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; VPF; VEGF; MVCD1; L-VEGF
Classification
Tumor Target Humanized Models,Immune Target Humanized Models,Cytokine Humanized Models,Full-Gene Humanized Models
Phenotype
Chromosome
2
Document
Note: When using this mouse strain in a publication, please cite “B6-hPD-1/hVEGFA mice (Catalog C001598) were purchased from Cyagen.”
Strain Description
The B6-hPD-1/hVEGFA mouse is a humanized model obtained by crossbreeding hPD-1 mice (Catalog No. C001524) with B6-hVEGFA mice (Catalog No. C001555). This model can be used for research in drug development, efficacy and safety evaluation, tumor immunotherapy evaluation, and immune system mechanisms related to human PD-1/VEGFA.
Application Area
Drug screening, efficacy evaluation, and safety assessment related to human PD-1/VEGFA
Tumor immunotherapy and mechanisms of the immune system
Validation Data