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Agxt KO
Product ID:
C001703
Background:
C57BL/6NCya
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Strain Description
The Agxt KO mouse is a gene knockout model created using gene-editing techniques to knock out the coding sequence of the Agxt gene (the homolog of the human AGXT gene) in mice. This model is used to research the pathogenic mechanisms of primary hyperoxaluria and develop related therapeutic strategies.
Application Area
Area
Studies of glyoxylate metabolism regulation
Area
Primary Hyperoxaluria pathogenesis and therapeutic drug evaluation
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