B6-hALB/hTFRC
Product Type
Age
Genotype
Sex
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Basic Information
Model Name
B6-hALB/hTFRC
Product ID
C001730
Background
C57BL/6NCya
Gene Alias
HSA; FDAHT; PRO0883; PRO0903; PRO1341; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Classification
Other Target Humanized Models
Chromosome
4
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Note: When using this mouse strain in a publication, please cite “B6-hALB/hTFRC mice (Catalog C001730) were purchased from Cyagen.”
Strain Description
B6-hALB/hTFRC mice are a dual gene humanized model of Alb and Tfrc, obtained by crossing B6-hALB (HSA) mice (Catalog number: C001492) with B6-hTFRC (CDS) mice (Catalog number: C001584). This model can be used for the development of ALB/TFRC-targeted therapeutic drugs, as well as for the research on drug development using human serum albumin (HSA) as a carrier or drug delivery across the blood-brain barrier (BBB), and for in vivo pharmacodynamic and pharmacokinetic studies.
Application Area
Development, screening, and efficacy evaluation of ALB/TFRC-targeted therapies
Design and evaluation of albumin carrier drugs
Research and evaluation of drug delivery across the blood-brain barrier (BBB).
Validation Data