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B6-hTFRC/htau
Product ID:
I001209
Background:
C57BL/6Cya
Documents:
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Basic Information
Model Name
B6-hTFRC/htau
Product ID
I001209
Gene Name
MAPT, TFRC
Background
C57BL/6Cya
Gene Alias
TAU; FTD1; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Classification
Full-Gene Humanized Models,Neurological Disease Models
NCBI ID
4137, 7037
Phenotype
MGI:97180, MGI:98822
Chromosome
17
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Rare Disease Data Center >>
Document
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Note
Note: When using this mouse strain in a publication, please cite “B6-hTFRC/htau mice (Catalog I001209) were purchased from Cyagen.”
Strain Description
The B6-hTFRC/htau mice are a model expressing human TFRC protein and tau protein, generated by crossing B6-hTFRC(CDS) mice (Catalog No.: C001584) with B6-htau mice (Catalog No.: C001410). These mice can be used for research on neurodegenerative diseases and iron metabolism disorders, as well as for the development and preclinical evaluation of TFRC/MAPT-targeted therapeutic agents.
Application Area
Area
Neurodegenerative diseases such as Alzheimer’s disease (AD) and frontotemporal dementia (FTD)
Area
Research on iron metabolism disorders and tumor development
Area
Preclinical studies of TFRC/MAPT-targeted therapeutic agents
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