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B6-hABCA4*c.5461-10T>C
Product ID:
I001210
Background:
C57BL/6JCya
Documents:
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Strain Description
The B6-hABCA4*c.5461-10T>C mouse is a humanized model of the Abca4 gene, where the mouse Abca4 gene has been replaced with the human ABCA4 gene carrying the c.5461-10T>C mutation using gene editing technology. This model can be used for research on various retinal degeneration diseases such as Stargardt disease (STGD), cone-rod dystrophy (CRD), and retinitis pigmentosa (RP).
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Area
Research on Stargardt Disease (STGD)
Area
Research on Cone-rod Dystrophy (CRD)
Area
Research on Retinitis Pigmentosa (RP)
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