This poster highlights Cyagen’s Human Genomic Ortholog (HUGO) mouse models, which enable detailed studies of human-specific biological processes and disease mechanisms. These models, including fully humanized genes such as hMAPT (with or without P301L/P301S mutations) and hMECP2-T158M, faithfully recapitulate key features of neurological disorders like Alzheimer’s disease, frontotemporal lobar degeneration, and Rett syndrome.

This brochure details Cyagen's comprehensive, end-to-end neuropharmacology CRO solutions. We provide the global neuroscience community with a full suite of services, from developing a wide range of neurological disease models to precise drug injection and thorough pharmacological analysis.

This pamphlet introduces Cyagen’s mouse models for human immune system reconstruction, featuring PBMC and HSC-based strategies validated in oncology, immunology, and infectious disease research.

This brochure provides a categorized overview of Cyagen’s Cre driver mouse lines, including constitutive, inducible, and fluorescent reporter combinations, with supporting validation data.

This pamphlet introduces Cyagen’s validated mouse models and full-spectrum CRO services for metabolic and cardiovascular research, including diabetes, obesity, MASH, and atherosclerosis.

This pamphlet introduces the HUGO-GT™ platform for next-generation humanized mouse models, enabling in situ replacement of mouse genes with full-length human orthologs for higher fidelity in disease modeling.