Herein, we have selected several high-impact factor (IF) publications from May through October 2020, which use custom genetically modified mouse models developed by Cyagen. These citations cover a broad range of research fields, including immunology, inflammation, cardiology, oncology, metabolomics, and epigenetics. 

Featured Animal Model Publications

Mouse Model Type Used

Research Applications

Gene Target(s)



TurboKnockout® Humanized Point Mutation (PM)

Leukemia, oncology, tumors

Gata2 (G320D)

C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia Through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

Cancer Cell

PMID: 32330454

Knockin (KI)


Epigenetics, metabolomics, oncology


SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways

Cancer Cell

PMID: 32619406

PNI-based Transgenic

Stem cells, coronary disease, internal ribosomal entry site (IRES)



The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis


PMID: 32674599

Knockout (KO)



The piRNA CHAPIR regulates cardiac hypertrophy by controlling METTL3-dependent N 6-methyladenosine methylation of Parp10 mRNA

Nature Cell Biology

PMID: 33020597

Conditional Knockout (cKO)

Immunology, Inflammation



Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition

Nature Immunology

PMID: 32807943


Genetically engineered animals remain essential for gaining proper understanding of human disease mechanisms and play an important role in a variety of research areas. Since our founding in 2005, Cyagen has been cited in over 4,000 publications – all of which are available as a searchable list: Browse All Citations


Year-End Savings Event – Up to 10% Off CAM Projects

Academic researchers are invited to save up to 10% on custom animal model (CAM) projects - offer ends December 18. Learn more about this offer by visiting the promotional page:

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About Cyagen

From vector and strategy design to animal model creation, cryopreservation, and breeding, Cyagen offers complete outsourcing for all animal model needs. Cyagen’s price matching policy guarantees you get the best deal. See how we can help further your research: contact us with your gene target(s) and our custom model generation experts will be in touch with you.