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B6-hLMNA
Product ID:
I001124
Background:
C57BL/6NCya
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Strain Description
This strain represents a mouse Lmna gene humanized model, in which the mouse Lmna gene is replaced by the human LMNA gene, including the 3'UTR. It can be employed to investigate the pathogenesis of neuromuscular diseases, heart disease, HGPS, and other disorders, as well as for preclinical evaluation of therapeutic drugs. Homozygous B6-hLMNA mice are viable and fertile.
Application Area
Area
Research on Hutchinson-Gilford Progeria Syndrome (HGPS)
Area
Research on neuromuscular diseases
Area
Research on cardiovascular diseases
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