B6-hATXN3
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Strain Description
This strain is a mouse Atxn3 gene humanized model that can be used for research on Spinocerebellar ataxia type 3 (SCA3). The homozygous B6-hATXN3 mice are viable and fertile.
Application Area
Research on Machado-Joseph disease (MJD, SCA3)
Preclinical evaluation of ATXN3-targeted drugs
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