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B6-hFUS*R521C
Product ID:
C001647
Background:
C57BL/6JCya
Documents:
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Strain Description
This model is a humanized model. Gene editing technology is used to replace the endogenous mouse Fus gene with a human FUS gene fragment carrying the R521C mutation. B6-hFUS*R521C mice can be used for the research of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration/dementia (FTLD).
Application Area
Area
Research on amyotrophic lateral sclerosis (ALS)
Area
Research on frontotemporal lobar degeneration/dementia (FTLD-FUS)
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