B6-hTFRC/Ube3a KO
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Genotype
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Basic Information
Model Name
B6-hTFRC/Ube3a KO
Product ID
C001737
Background
C57BL/6NCya
Gene Alias
Hpve6a; 4732496B02; 5830462N02Rik; A130086L21Rik; T9; TR; TFR; p90; CD71; TFR1; TRFR; IMD46
Classification
Other Target Humanized Models,Neurological Disease Models,Rare Disease Models
Phenotype
Chromosome
7
Document
Note: When using this mouse strain in a publication, please cite “B6-hTFRC/Ube3a KO mice (Catalog C001737) were purchased from Cyagen.”
Strain Description
The B6-hTFRC/Ube3a KO mice are generated by crossing B6-hTFRC(CDS) mice with Ube3a KO mice. These mice can be used for studying the pathogenesis of Angelman syndrome (AS), developing related therapeutic approaches, and conducting preclinical research on TFRC-targeted drugs.
Application Area
Research on the pathogenic mechanisms and therapeutic drugs of Angelman Syndrome (AS)
Other neurological system studies
Validation Data