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B6-Fgfr3*Y367C
Product ID:
C001745
Background:
C57BL/6NCya
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Strain Description
B6-Fgfr3*Y367C mice are obtained by introducing the Y367C mutation into the mouse Fgfr3 gene using gene editing technology. Internal preliminary data show that homozygous B6-Fgfr3*Y367C mice die at 3 weeks. This model can be used to study the mechanisms and therapeutic approaches for diseases such as achondroplasia (ACH) and thanatophoric dysplasia (TD).
Application Area
Area
Research on the disease mechanisms and treatment methods of achondroplasia (ACH) and thanatophoric dysplasia (TD), etc.
Area
Research on Fgfr3 Y367C antagonist
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