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B6-APOE4/htau*P301L
Product ID:
C001888
Background:
C57BL/6N;6JCya
Documents:
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Basic Information
Model Name
B6-APOE4/htau*P301L
Product ID
C001888
Gene Name
APOE, MAPT
Background
C57BL/6N;6JCya
Gene Alias
AD2; LPG; APO-E; ApoE4; LDLCQ5; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6
Classification
Full-Gene Humanized Models,Neurological Disease Models,Rare Disease Models
NCBI ID
348, 4137
Phenotype
MGI:88057, MGI:97180
Chromosome
--
More
Rare Disease Data Center >>
Datasheet
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Note
Note: When using this mouse strain in a publication, please cite “B6-APOE4/htau*P301L mice (Catalog C001888) were purchased from Cyagen.”
Strain Description
The B6-APOE4/htau*P301L mouse is a model generated by crossing B6-APOE4 mice with B6-htau*P301L mice. It can be used to study the pathogenic mechanisms and therapeutic approaches of neurodegenerative diseases such as Alzheimer’s disease (AD), frontotemporal dementia (FTD), and cerebral amyloid angiopathy (CAA), as well as cardiovascular diseases such as atherosclerosis.
Application Area
Area
Research on neurodegenerative diseases such as Alzheimer’s disease (AD), frontotemporal dementia (FTD), and cerebral amyloid angiopathy (CAA)
Area
Research on cardiovascular diseases such as atherosclerosis
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