C57BL/6NCya-Acod1em1/Cya
Common Name:
Acod1-KO
Product ID:
S-KO-02679
Background:
C57BL/6NCya
Product Type
Age
Genotype
Sex
Quantity
Price:
Contact for Pricing
Basic Information
Strain Name
Acod1-KO
Strain ID
KOCMP-16365-Acod1-B6N-VA
Gene Name
Product ID
S-KO-02679
Gene Alias
CAD; Irg1
Background
C57BL/6NCya
NCBI ID
Modification
Conventional knockout
Chromosome
14
Phenotype
Datasheet
Application
--
Note: When using this mouse strain in a publication, please cite “C57BL/6NCya-Acod1em1/Cya mice (Catalog S-KO-02679) were purchased from Cyagen.”
Strain Description
Ensembl Number
ENSMUST00000022722
NCBI RefSeq
NM_008392
Target Region
Exon 2~4
Size of Effective Region
~3.3 kb
Quality Control Standard
Sperm Test
Pre-cryopreservation: Measurement of sperm concentration, determination of sperm viability.
Post-cryopreservation: A vial of cryopreserved sperms is selected for in-vitro fertilization from each batch.
Environmental Standards:SPF
Available Region:Global
Source:Cyagen
References
CELLULAR & MOLECULAR IMMUNOLOGY
May, 2024
Neutrophil-macrophage communication via extracellularvesicle transfer promotes itaconate accumulation andameliorates cytokine storm syndrome
Read More
Genes & Diseases
May, 2022
Protective effects of IRG1/itaconate on acute colitis through the inhibition of gasdermins-mediated pyroptosis and inflammation response
Read More
Cell Death & Disease
Jul, 2023
Negative regulation of pro-apoptotic AMPK/JNK pathway by itaconate in mice with fulminant liver injury
Read More
European Journal of Inflammation
Mar, 2024
Irg1/itaconate activates Nrf2/HO-1 pathway and mitigates septic liver injury in mice
Read More
预印本
Sep, 2023
Immune-response gene 1 deficiency aggravates inflammation-triggered cardiac dysfunction by inducing M1 macrophage polarization and aggravating Ly6C high monocyte recruitment
Read More