Gaa KO
Product Type
Age
Genotype
Sex
Quantity
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Basic Information
Model Name
Gaa KO
Product ID
C001702
Gene Name
Background
C57BL/6JCya
Gene Alias
E430018M07Rik
Classification
Metabolic Disease Models,Rare Disease Models
NCBI ID
Phenotype
Chromosome
11
Document
Note: When using this mouse strain in a publication, please cite “Gaa KO mice (Catalog C001702) were purchased from Cyagen.”
Strain Description
The Gaa KO mouse is a gene knockout model created using gene-editing techniques to knock out the coding sequence of the Gaa gene (the homolog of the human GAA gene) in mice. This model is used to research the pathogenic mechanisms of Glycogen Storage Disease Type II (Pompe disease) and develop related therapeutic strategies.
Application Area
Studies of lysosomal glycogen metabolism
Research on Glycogen Storage Disease Type II (Pompe disease) pathogenesis and therapeutic drug evaluation
Validation Data