Gaa KO
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Strain Description
The Gaa KO mouse is a gene knockout model created using gene-editing techniques to knock out the coding sequence of the Gaa gene (the homolog of the human GAA gene) in mice. This model is used to research the pathogenic mechanisms of Glycogen Storage Disease Type II (Pompe disease) and develop related therapeutic strategies.
Application Area
Studies of lysosomal glycogen metabolism
Research on Glycogen Storage Disease Type II (Pompe disease) pathogenesis and therapeutic drug evaluation
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