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Research Trends
Obesity Research Mice Introduction (Part 2): Non-LEP/LEPR Genetic Models
Feb 18, 2024
In our previous article, we provided an “Introduction to Murine Models of Obesity (Part 1): LEP/LEPR Classic Pathway Model”. In this edition, we will delve into non-LEP/LEPR genetic mouse models for obesity research. Read More >
Research Trends
Introduction to Murine Models of Obesity (Part 1): LEP/LEPR Classic Pathway Model
Jan 31, 2024
To effectively conduct research on obesity and its prevention and treatment, it is crucial to comprehend the mechanisms underlying obesity. Leveraging mouse models of obesity-related diseases is essential for gaining meaningful insights into the prevention and treatment of obesity and its complications. Read More >
Research Trends
Challenges of Performing Orthotopic Colorectal Cancer Modeling: Evaluating the Effectiveness of Modeling Site Exploration
Jan 26, 2024
Colorectal cancer is a common malignant tumor that occurs in the colon, predominantly in the junction between the rectum and sigmoid colon. It ranks as the third most common gastrointestinal tumor with the highest incidence in the age group of 40 to 50 years, with a male-to-female ratio of 2-3:1. Read More >
Research Trends
Circumventing Difficulties in Dynamic Monitoring of Orthotopic Tumor Transplantation Models with In Vivo Bioluminescent Imaging
Jan 12, 2024
Compared to the traditional method of euthanizing animals in batches to obtain experimental data, real-time bioluminescence imaging (BLI) technology allows for qualitative and quantitative observations at the cellular and molecular levels of a living organism. Read More >
Research Trends
Breaking Stereotypes: Diabetes Research, GLP-1, and the Roadmap for Preclinical Studies
Dec 18, 2023
On November 14th, World Diabetes Day serves as a global call to action to confront the complexities of diabetes, a condition that often grapples with various stereotypes and misconceptions. It's a common misbelief that only overweight individuals are at risk of diabetes or that young people need not be concerned about it. Read More >
Research Trends
Age-Related Health Challenges in Lab Rats: A Comprehensive Examination
Dec 11, 2023
In this issue, we will be discussing another factor that is often overlooked but can significantly impact rat health — age. Get ready to learn more about the impacts of rodent age on health! Read More >
Research Trends
High-Quality Adeno-Associated Virus (AAV) Packaging
Dec 04, 2023
In the rapidly advancing field of gene therapy, the efficiency and reliability of adeno-associated virus (AAV) vectors play a pivotal role in driving groundbreaking research and therapeutic developments. At Cyagen, we stand at the forefront of this revolution, offering a comprehensive suite of AI-assisted AAV production services designed to streamline your experimental process and elevate your research to new heights. Our commitment to excellence extends across the entire spectrum of AAV production, from vector design and construction to virus packaging, purification, expression analysis, and functional validation. Read More >
Research Trends
Ensuring Optimal Well-being for Lab Mice: A Guide to Daily Observation and Care
Nov 21, 2023
In the realm of biomedical research, mice are widely used for various experiments. To guarantee their well-being and enhance the precision of experiments, it is imperative to dedicate time and attention to their daily care. This article delves into the nuances of maintaining mouse health, shedding light on key aspects of daily care and observation that significantly impact the success of scientific endeavors. Read More >
Research Trends
What are rare immunological diseases? Exploring the Advantages of C-NKG Severe Immunodeficient Mice
Nov 03, 2023
Do you recall the famous "Bubble Boy"? Poor David suffered from Severe Combined Immunodeficiency (SCID), which made him incapable of combatting any bacteria or viruses, forcing him to spend his entire life in a sterile environment. Shortly after his birth, doctors placed him into a sterile bubble, hence the term "Bubble Boy" for people with similar conditions. Today, let's delve deeper into immunodeficiency disorders. Read More >
Research Trends
Congenital Genetic Abnormalities & Related Phenotypes in Rat Models of Human Diseases
Oct 27, 2023
In addition to factors related to routine husbandry practices, rats are also susceptible to various genetic diseases, known as congenital genetic abnormalities. Today, we will introduce some congenital genetic abnormalities commonly seen in rats. Read More >