B6-APOE4/htau*P301S
Product Type
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Genotype
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Basic Information
Model Name
B6-APOE4/htau*P301S
Product ID
C001832
Background
C57BL/6Cya
Gene Alias
AD2; LPG; APO-E; ApoE4; LDLCQ5; TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6
Classification
Full-Gene Humanized Models,Neurological Disease Models,Rare Disease Models
Chromosome
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Datasheet
Note: When using this mouse strain in a publication, please cite “B6-APOE4/htau*P301S mice (Catalog C001832) were purchased from Cyagen.”
Strain Description
The B6-APOE4/htau*P301S mice are a model obtained by crossing B6-APOE4 mice with B6-htau*P301S mice. This model can be used for the research on the pathogenic mechanisms and treatment methods of neurodegenerative diseases such as Alzheimer's disease (AD) and progressive cerebral amyloid angiopathy (CAA), as well as cardiovascular diseases such as atherosclerosis.
Application Area
Research on neurodegenerative diseases such as Alzheimer's Disease (AD) and progressive cerebral amyloid angiopathy (CAA)
Research on cardiovascular diseases, such as atherosclerosis
Validation Data