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45 Results Retrieved With “Trp53”
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Trp53 KO
Product ID:
C001203
Strain:
C57BL/6JCya
Status:
Description:
This strain is a mouse model lacking Trp53, which is a gene homologous to human TP53. Homozygous Trp53-KO male mice develop normally but are prone to spontaneous tumors. Homozygous Trp53-KO mice developed tumors, mainly lymphomas, and sarcomas, at three to six months of age, and heterozygous mice developed tumors at about 10 months of age. Homozygous males are viable and fertile, but homozygous females have reduced survival at weaning.
This strain is a mouse model lacking Trp53, which is a gene homologous to human TP53. Homozygous Trp53-KO male mice develop normally but are prone to spontaneous tumors. Homozygous Trp53-KO mice developed tumors, mainly lymphomas, and sarcomas, at three to six months of age, and heterozygous mice developed tumors at about 10 months of age. Homozygous males are viable and fertile, but homozygous females have reduced survival at weaning.
C57BL/6JCya-Trp53em1/Cya
Product ID:
S-KO-05566
Strain:
C57BL/6JCya
Status:
Description:
Trp53 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Trp53 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Trp53 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Trp53em1/Cya
Product ID:
S-KO-05567
Strain:
C57BL/6JCya
Status:
Description:
Trp53 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Trp53 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Trp53 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Trp53em1/Cya
Product ID:
S-KO-16097
Strain:
C57BL/6NCya
Status:
Description:
Trp53 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Trp53 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Trp53 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6NCya-Trp53em1flox/Cya
Product ID:
S-CKO-06451
Strain:
C57BL/6NCya
Status:
Description:
Trp53 is located on chromosome 11 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Trp53 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
Trp53 is located on chromosome 11 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Trp53 conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Trp53em1flox/Cya
Product ID:
S-CKO-06450
Strain:
C57BL/6JCya
Status:
Description:
Trp53 is located on chromosome 11 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Trp53 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53 is located on chromosome 11 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Trp53 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Trp53em1flox/Cya
Product ID:
S-CKO-06449
Strain:
C57BL/6JCya
Status:
Description:
Trp53 is located on chromosome 11 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Trp53 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53 is located on chromosome 11 of mice. SgRNA and ssDNA were designed using Nuclease Technology; Trp53 conditional knockout mice were obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Trp53i13em1/Cya
Product ID:
S-KO-05236
Strain:
C57BL/6JCya
Status:
Description:
Trp53i13 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Trp53i13 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53i13 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Trp53i13 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Trp53i11em1/Cya
Product ID:
S-KO-08941
Strain:
C57BL/6JCya
Status:
Description:
Trp53i11 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Trp53i11 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53i11 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Trp53i11 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Trp53rkaem1/Cya
Product ID:
S-KO-09757
Strain:
C57BL/6JCya
Status:
Description:
Trp53rka is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Trp53rka knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
Trp53rka is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Trp53rka knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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