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Animal Models
C57BL/6JCya-Gptem1/Cya
Gpt is located on chromosome 15 of mice. Nuclease Technology was used to design sgRNA; Gpt knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Dptem1/Cya
Dpt is located on chromosome 1 of mice. Nuclease Technology will be used to design sgRNA; Dpt knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ptnem1/Cya
Ptn is located on chromosome 6 of mice. Nuclease Technology was used to design sgRNA; Ptn knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pthem1/Cya
Pth is located on chromosome 7 of mice. Nuclease Technology was used to design sgRNA; Pth knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Nptnem1/Cya
Nptn is located on chromosome 9 of mice. Nuclease Technology was used to design sgRNA; Nptn knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ptenem1/Cya
Pten is located on chromosome 19 of mice. Nuclease Technology was used to design sgRNA; Pten knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ptk2em1/Cya
Ptk2 is located on chromosome 15 of mice. Nuclease Technology was used to design sgRNA; Ptk2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Pterem1/Cya
Pter is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Pter knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Bptfem1/Cya
Bptf is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Bptf knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Jpt1em1/Cya
Jpt1 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Jpt1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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