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Animal Models
C57BL/6JCya-Btcem1/Cya
Btc is located on chromosome 5 of mice. Nuclease Technology was used to design sgRNA; Btc knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Cltcem1/Cya
Cltc is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Cltc knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ftcdem1/Cya
Ftcd is located on chromosome 10 of mice. Nuclease Technology was used to design sgRNA; Ftcd knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Tcl1em1/Cya
Tcl1 is located on chromosome 12 of mice. Nuclease Technology was used to design sgRNA; Tcl1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Stc1em1/Cya
Stc1 is located on chromosome 14 of mice. Nuclease Technology will be used to design sgRNA; Stc1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Rtcbem1/Cya
Rtcb is located on chromosome 10 of mice. Nuclease Technology will be used to design sgRNA; Rtcb knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Stc2em1/Cya
Stc2 is located on chromosome 11 of mice. Nuclease Technology was used to design sgRNA; Stc2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Ttc3em1/Cya
Ttc3 is located on chromosome 16 of mice. Nuclease Technology will be used to design sgRNA; Ttc3 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Btcem1/Cya
Btc is located on chromosome 5 of mice. Nuclease Technology will be used to design sgRNA; Btc knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Cltcem1/Cya
Cltc is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Cltc knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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