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Animal Models
C57BL/6JCya-Swi5em1/Cya
Swi5 is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Swi5 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wif1em1/Cya
Wif1 is located on chromosome 10 of mice. Nuclease Technology was used to design sgRNA; Wif1 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Swi5em1/Cya
Swi5 is located on chromosome 2 of mice. Nuclease Technology was used to design sgRNA; Swi5 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wipi2em1/Cya
Wipi2 is located on chromosome 5 of mice. Nuclease Technology was used to design sgRNA; Wipi2 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Zwintem1/Cya
Zwint is located on chromosome 10 of mice. Nuclease Technology was used to design sgRNA; Zwint knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Zswim6em1/Cya
Zswim6 is located on chromosome 13 of mice. Nuclease Technology was used to design sgRNA; Zswim6 knockout mice were obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wizem1flox/Cya
Wiz is located on chromosome 17 of mice. SgRNA and ssDNA will be designed using Nuclease Technology; Wiz conditional knockout mice will be obtained by high-throughput electroporation of fertilized eggs. After sexual maturity, sperm will be collected for cryopreservation.
C57BL/6JCya-Wipf2em1/Cya
Wipf2 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Wipf2 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wipi1em1/Cya
Wipi1 is located on chromosome 11 of mice. Nuclease Technology will be used to design sgRNA; Wipi1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
C57BL/6JCya-Wipf1em1/Cya
Wipf1 is located on chromosome 2 of mice. Nuclease Technology will be used to design sgRNA; Wipf1 knockout mice will be obtained by applying high-throughput electroporation of fertilized eggs. After sexual maturity, sperm were collected for cryopreservation.
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Global Antibody Drug Industry Development BlueBook (Frost & Sullivan)
Key Insights
The industry is undergoing a rapid transformation driven by next-generation modalities, globalized markets, and upstream technological innovations.
  • Market Structural Shift: Monoclonal antibodies drive steady growth, but ADCs and bispecifics are rapidly accelerating, reshaping the market with higher-value innovations.
  • Chinese Market Globalization: China is actively expanding globally, evidenced by a surge in high-value cross-border license-out deals.
  • Technology-Driven Efficiency: Advanced discovery engines—exemplified by Cyagen's HUGO-Ab platform and AI algorithms—are streamlining candidate screening, optimizing molecular design, and localizing the upstream supply chain.
  • Oncology-Focused Innovation: R&D pipelines remain heavily concentrated on high-incidence malignancies like non-small cell lung cancer, utilizing complex modalities to combat clinical resistance.
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